临床药师参与55例四肢骨折内固定术后感染的药物治疗回顾与分析

Review and Analysis of Clinical Pharmacist Participating in Drug Therapy for 55 Infection Cases after Internal Fixation for Limb Fracture

目的:总结临床药师参与四肢骨折内固定术后感染患者的药物治疗实践,探讨治疗骨折内固定术后感染的有效方法。方法:对55例骨折内固定术后感染患者行抗感染、内固定拆除、局部抗生素骨水泥应用、扩创及持续冲洗引流等处理。临床药师根据患者的病情变化,提供咨询意见,与临床医师协商,制订针对性的治疗方案,并随时调整。结果:术后随访平均2年(10个月～4年2个月),2例截肢,4例不愈合,49例患者愈合。结论:临床药师参与药物治疗实践,对患者的药物治疗有帮助。

OBJECTIVE： To summarize the experience of clinical pharmacist participating in drug therapy for infection case after internal fixation for limbs fracture, and to discuss effective treatment methods for postoperative infection of internal fixation for bone fractures. METHODS： 55 eases of postoperative infection of internal fixation for limbs fracture were given anti-infection administration, internal fixator removal, local bone cement administration, local irrigation and continuous drainage. Clinical pharmacists provided advice and consulted with clinicians to develop and adjust targeted treatment programs, according to patient＇ s condition. RESULTS： Following up for average 2 year （10 months-4 years and 2 months）, 49 cases were healed, 4 cases were ineffective and 2 cases were amputated. CONCLUSION： The participation of clinical pharmacists in drug therapy contributes to drug treatment.