摘要
合成了杂多酸环戊二烯钒衍生物[Bu4N]4[(CpV)PW11O39](1),[Bu4N]4H[(CpV)SiW11O39](2)和[Bu4N]4[A-β-(η5-CpV)SiW9V3O40](3),并通过元素分析、IR、51 V和183 W NMR谱进行了结构表征。结果表明配合物(1)和(2)为结合型有机金属配合物,(3)为支撑型杂多酸有机金属配合物。体外抗肿瘤活性研究表明化合物(1)对HL-60和B16均具有一定的抑制作用。
Cyclopentadienylvanadium derivatives of polyoxotungstates 4[(CpV)PW11O39](1),4H[(CpV)SiW11O39](2) and 4[A-β-(η5-CpV)SiW9V3O40](3) were synthesized,and characterized by elemental analysis,IR,51V and 183W NMR spectroscopy.Experiment results indicate that(1) and(2) are polyoxometalate-incorporated organometallic complexes,and(3) is a polyoxometalate supported organometallic complex.Antitumoral activities were examined by MTT method.Experiment results indicate that the title complexes did exhibit to a certainty antitumor activity for HL-60 and B16.
出处
《光谱学与光谱分析》
SCIE
EI
CAS
CSCD
北大核心
2012年第9期2512-2514,共3页
Spectroscopy and Spectral Analysis
基金
国家自然科学基金项目(20472013)资助
关键词
杂多酸
环戊二烯钒衍生物
支撑型
结合型
有机金属配合物
抗肿瘤活性
Polyoxotungstate; Cyclopentadienylvanadium derivatives; Supported; Incorporated; Organometallic complexes; Antitumoral activities;