从肝论治2型糖尿病的临床研究

Clinical Study in Treating Type 2 Diabetes Mellitus According to Liver in TCM

目的 :探讨用中药丹栀逍遥散从肝论治 2型糖尿病的临床疗效。方法 :51例 2型糖尿病患者在常规治疗的基础上分为两组 :对照组 2 0例 (常规药物治疗 )和治疗组 31例 (常规药物加用丹栀逍遥散治疗 )。疗程 3个月 ,治疗前后观察空腹血糖 (FBG)、空腹血胰岛素 (Ins)、糖化血红蛋白 (HbA1c)、血脂 (CH、TG)等指标。结果 :治疗组疗效优于对照组 (P <0 0 5) ;治疗组治疗后FBG、Ins、HbA1c比治疗前、对照组治疗后均有改善 (P <0 0 5)。结论 :疏肝解郁、调畅情志可以作为糖尿病治疗的有效辅助方法。

To explore the clinical effect of Danzhi Xiaoyao powder (DZXY) in treating type 2 diabetes mellitus (DM) according to Liver in TCM. Methods: Fifty one type 2 DM patients were randomly divided into the treated group and the control group, 31 patients of the treated group were treated with conventional and DZXY therapy, while 20 patients in the control were treated with conventional therapy alone. Before and after treatment for 3 months, the levels of fasting blood glucose (FBG), fasting insulin, glycosylated hemoglobin (HbA1c), blood cholesterol (CH) and triglycerides (TG) were examined in all the patients. Results: By the end of 3 months, the effect in treating type 2 DM in the treated group was better than that in the control group (P<0 05). Compared with those before treatment in each group and those of the control ,the levels of FBG, fasting insulin, HbA1c after DZXY treatment were reduced (P<0 05), but levels of CH and TG in all groups had no significant difference. Conclusion: DZXY could sooth the Liver to relieve depression, which is effective in treating type 2 DM and could improve the symptoms of DM patients.