高压氧联合细胞生长肽治疗新生儿缺氧缺血性脑病64例临床分析

Clinical analysis of hyperbaric oxygen combined with cell growth peptide in the treatment of 64 cases of newborns with hypoxic ischemic encephalopathy

目的探讨高压氧联合细胞生长肽治疗新生儿缺氧缺血性脑病的临床效果。方法将我院收治的68例新生儿缺氧缺血性脑病患儿随机分为对照组和观察组,每组各34例。对照组采用高压氧治疗,观察组在对照组的基础上加用细胞生长肽治疗。分析两组的治疗效果及患儿智能发育情况。结果观察组总有效率显著优于对照组,差异有统计学意义(P<0.05)。观察组患儿智能发育情况优于对照组,差异有统计学意义(P<0.05)。结论采用高压氧联合细胞生长肽治疗新生儿缺氧缺血性脑病,疗效优于单用高压氧治疗,使用方便,值得临床推广应用。

Objective To study the clinical effect of the hyperbaric oxygen combined with cell growth peptide in the treat- ment of newborns with hypoxic ischemic encephalopathy. Methods 68 cases of newborns with hypoxic ischemic en- cephalopathy were randomly divided into the control group and the observation group, each group had 34 cases. The con- trol group was given hyperbaric oxygen therapy, the observation group was combined with cell growth peptide treatment on the basis of the control group. The treatment effect and newborns＂ intelligence development situation of the two groups were analyzed. Results The total effective rate of the observation group was significantly better than that of the control group, the difference was statistically significant （P 〈 0.05）. The intelligence development situation in the observation group was better than that in the control group, the difference was statistically significant （P 〈 0.05）. Conclusion The effect of hyperbaric oxygen combined with cell growth peptide in the treatment of newborns is better than hyperbaric oxygen therapy, which is easy to use, and it is worthy of application in clinic.