胎心监护联合胎儿大脑中动脉血流S/D值、血清雌三醇检测评估新生儿预后的临床应用

Clinical application of fetal heart rate monitoring combined with middle cerebral artery blood flow S/D value and serum estriol detection in assessment of neonatal prognosis

目的探讨胎心监护联合胎儿大脑中动脉血流S/D值、血清雌三醇检测评估新生儿预后的临床应用。方法对2009年7月~2012年1月在我科分娩的2 450例孕妇进行胎心监护及血清雌三醇、胎儿大脑中动脉血流S/D值测定,分析其与新生儿预后的关系。结果一种检查方法的假阳性率为27.9%,两种联合检查假阳性率为5.4%,三种联合检查的假阳性率为0.6%,明显低于一种及两种联合检测（P〈0.05）。结论多因素联合监测发现胎儿窘迫的假阳性率减少,可降低剖宫产率并降低新生儿的并发症发生率。

Objective To discuss the clinical application of fetal heart rate monitoring combined with middle cerebral artery blood flow S/D value and serum estriol detection in assessment of neonatal prognosis. Methods 2 450 cases of deliv- ery pregnant women in our deparmtent from July 2009 to January 2012 were selected and performed the fetal heart rate monitoring, middle cerebral artery blood flow S/D value and serum estriol detection. Then the relationship between detec- tion results and neonatal prognosis was analyzed. Results The false-positive rate of single detection was 27.9%; the false- positive rate of two combination detection was 5.4%; the false-positive rate of three combination detection was only 0.6%; the false positive rate of three combination detection was significantly lower than others （P 〈 0.05）. Conclusion The false- positive rate of fetal distress found by multi-factors combined monitoring is less, which can reduce cesarean section rate and the complications of newborn babies.