期刊文献+

充血性心力衰竭基因治疗的研究进展 被引量:3

下载PDF
导出
摘要 充血性心力衰竭是各种心血管疾病的严重或终末阶段 ,目前临床药物治疗并未达到理想的要求 ,心脏移植也有一定的局限性。分子生物学研究认为心衰的本质是心肌组织细胞中某些相关基因表达与调控异常的结果 ,经基因导入以延缓和纠正心肌组织某些基因的改变 ,有可能使心衰治疗获得较大突破。
出处 《国外医学(生理病理科学与临床分册)》 2000年第4期297-299,共3页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
  • 相关文献

参考文献10

  • 1Nabel EG. Circulation . 1995
  • 2Rothmann T,Katus HA,Hartong R,et al. Gene Therapy . 1996
  • 3Murry CE,Schwartz SM,Hauschka SD,et al. The Journal of Clinical Investigation . 1996
  • 4Bing OH. Journal of Molecular and Cellular Cardiology . 1994
  • 5Sharov VG,Goldstein S,Lesch M,et al. American Journal of Pathology . 1996
  • 6Kirshenbaum LA,Moissac D. Circulation . 1997
  • 7Delvaux A,Velu T,Goldman M,et al. Transplantation . 1994
  • 8Raju GP,Eisen HJ,Belland SE. Transplantation . 1994
  • 9Hajjar RJ,Kang JX,Gwathmey JK,et al. Circulation . 1997
  • 10Chien KR,Grace AA,Minamisawa S,et al. Japanese Circulation Journal . 1997

同被引文献35

  • 1Lonn Em,Yusu fs,Jba P,et al.Emergingrole of angiotensin-converting enzyme inhibitors in Cardiac and Vascular proection.Circulation,1994,90:2056-2069.
  • 2Williams M L.Targeted -? adrenergic.receptor kinase (? ARK1) inhibition by gene etransfer in failiing.human hearts.Circulation 2004,109:1590-1593.
  • 3Maack C,Elter T,Nickenig G,et al.Prospective crossover comparison of carvedilol and metoprolol in patients with chronic heart failure.Am Coll Cardiol,2001,38:939-946.
  • 4Patrick M,Carmen E,Mirko V,et al.Hope for a broken heart? Trends in Biotechenology,2004,22:487-489.
  • 5Xiao RP,Zhu W,Zheng M,et al.Subtype-specific beta-adrenoceptor signaling,Path ways in the heart and their potential clinical implications.Eur Heart J,2004,25:358-365.
  • 6Poole-wilsion.Comparision of carvediol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvediol Or Metprolol Europen Trial (COMET):radiomised.controlled.Trial.Lancent,2003,362:7-13.
  • 7WeberkT,sun Y,Wodi LA,et al.Toward a broader understanding of aldosterone in congestive heart failure.J Renin Angiotensin Aldosterone Syst,2003,4:155-163.
  • 8Pitt B,Remme W,Zannad F,et al.Eplenrenore,a selective aldosterone blocker,in patients with left ventricular dysfunction after myocardial infarction.N Engl J Med,2003,348:1309-1321.
  • 9Levy DG,Rocha R,Funder JW.Distinguishing the antihypertensive and electrolyte effects of eplerenone.J Clin Endocrinol Metab,2004,89:2736-2740.
  • 10Weinberger MH.Eplerenone:a new selective aldosterone receptor antagonist.Drugs Today(Barc),2004,40:481-485.

引证文献3

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部