摘要
肿瘤耐药和细胞凋亡是目前肿瘤研究的两个热点 ,大量研究表明化疗药物可以通过诱导细胞凋亡而杀伤肿瘤细胞 ,细胞凋亡的抑制可导致肿瘤耐药的产生 ,本文对
出处
《国外医学(药学分册)》
2000年第4期214-216,共3页
Foreign Medical Sciences(Section of Pharmarcy)
参考文献10
-
1Doyle LA,Yang W,Abruzzo LV,et al.A multidrug resistance transporter from human MCF-7 breast cancer cells[].Proceedings of the National Academy of Sciences of the United States of America.1998
-
2Bray PG,Ward SA.A comparison of phenomenology and genetics of multidrug resistance in cancer cells and quinoline resistance in Plasmodium falciparum[].Pharmacology and Therapeutics.1998
-
3Kaufmann SH,Desnoyers S,Ottaviano Y,et al.Specific proteolytic cleavage of poly ( ADP-ribose )polymerase: an early marker of chemotherapyinduced apoptosis[].Cancer Research.1993
-
4Kroemer G,Dallaporta B,Resche-Rigon M,et al.The mitochondrial death life regulator in apoptosis and necrosis[].Annual Review of Physiology.1998
-
5Hannun YA.Apoptosis and the dilemma of cancer chemotherapy[].Blood.1997
-
6Johnstone RW,Cretney E,Smyth MJ.P-glycoprotein protects leukemia cells against caspase-dependent , but not caspase-independent cell death[].Blood.1999
-
7Drach J,Gsur A,Hamilton G,et al.Involvement of P-glycoprotein in the transmembrane transport of interleukin-2 ( IL-2 ), IL-4, and interferon-gamma in normal human T lymphocytes[].Blood.1996
-
8Kroemer G,de The H.Arsenic trioxide, a novel mitochondriotoxic anticancer agent ?[].Journal of the National Cancer Institute.1999
-
9Hoffman MM,Roepe PD.Analysis of ion transport pertubations caused by hu MDR1 protein overexpression[].Biochemistry.1997
-
10Li P,Nijhawan D,Budihardjo I,et al.Cytochrome C and dATP-dependent formation of Apaf -1 caspase-9 complex initiates an apoptotic protease cascade[].Cell.1997
同被引文献15
-
1曾小莉,涂植光.人参皂甙Rh_2对人肝癌细胞SMMC-7721的诱导分化作用[J].癌症,2004,23(8):879-884. 被引量:41
-
2曾小莉,涂植光.人参皂甙Rh_2对人肝癌细胞SMMC-7721信号传导的影响[J].中华肝脏病杂志,2004,12(9):565-566. 被引量:22
-
3王占峰 ,罗毅男 ,洪新雨 ,鞠砚 ,孙玉芹 ,韩海铃 .人参皂甙Rh2抗肿瘤作用机制的研究[J].北华大学学报(自然科学版),2005,6(1):50-52. 被引量:13
-
4Cottton- Carlo C, et al. Expression of the mulfidrug resistance gene product(P- glycoprotein) in htanan nomml and tumor fissues.Md Cell cytochem,1990, 38; 1277- 1287.
-
5El Hafny B, et al. Role of P - glyceprotein in eolehieine and vinblastine cellular kinetics in an immortalized rat biain mierovessel endothelial cell line. Bioehem Pharmacol, 1997, 53 (11): 1735- 1743.
-
6Hefmann EJ, et al. Expression and functional activity of P - glycoprotein in cultured cerebral capillary endothelial cells.Cancer Res, 1992, 52 (24);6969 - 6976.
-
7A.Philchenkov.Caspases:potential targets for regulating cell death[J].Cell.Mol.Med.2004,8(4):432
-
8王金华,叶祖光,孙爱续,薛宝云,梁爱华,李春英,王岚.粉防己碱逆转人乳腺癌MCF-7多药耐药细胞的抗凋亡作用[J].中国中药杂志,2002,27(1):46-50. 被引量:31
-
9徐强.Caspases与调亡及心肌缺血再灌注损伤[J].第三军医大学学报,2001,23(A06):148-149. 被引量:1
-
10黄雌友,文格波,曹仁贤,刘江华.葡萄糖对人血管内皮细胞周期和凋亡的影响[J].南华大学学报(医学版),2002,30(4):331-334. 被引量:4
引证文献2
-
1杨汝春,鲁盈,朱晓玲,王军,张迎华,林宜.葡萄糖对SVAREC细胞P-糖蛋白转运和表达的影响[J].医学研究通讯,2004,33(12):35-37. 被引量:1
-
2张晖,孔棣,吴咸中,张会来,王华庆.人参皂甙Rh_2致MCF-7/ADM凋亡的实验研究[J].中国中西医结合外科杂志,2007,13(3):261-264. 被引量:6
二级引证文献7
-
1吕发展,马东旺.人参用于肿瘤耐药治疗中的研究进展[J].现代中西医结合杂志,2008,17(24):3885-3886. 被引量:3
-
2蔡康荣,蔡春.维甲酸与人参皂甙-Rh_2或半边旗二萜类化合物5F协同诱导肝癌细胞凋亡的研究[J].中国现代医学杂志,2008,18(19):2788-2791. 被引量:2
-
3杨慧科,吕艳华,刘慧冬,王强,李晓冬,李玉兰,赵玲辉.人参皂甙Rh2对小鼠移植瘤血管内皮生长因子C及淋巴管生成的影响[J].解剖学报,2009,40(2):265-268. 被引量:5
-
4孔繁利,李凤娥,孙新,芦丽莉,邵月婷,赵雪俭,李玉林.人参皂甙Rh_2与DDP抗PC-3协同作用的实验研究[J].现代预防医学,2009,36(22):4308-4310. 被引量:2
-
5程春,何志贤,王华.人参皂苷Rh_2抗肿瘤细胞作用研究进展[J].交通医学,2010,24(1):23-25. 被引量:8
-
6杨汝春,王永钧,鲁盈,厉春萍,朱晓玲.IgA肾病患者肾小管中P-gp表达与肾脏病理及肾功能损害的相关性[J].浙江医学,2011,33(10):1453-1455.
-
7谢炜,罗阔,韩萍.人参皂苷Rh2对肝癌细胞表皮生长因子受体表达水平的影响[J].免疫学杂志,2013,29(6):490-493. 被引量:5
-
1Dong-Yu Wang,Ya-Nan Wu,Jun-Qi Huang,Wei Wang,Meng Xu,Jin-Peng Jia,Gang Han,Bei-Bei Mao,Wen-Zhi Bi.Hippo/YAP signaling pathway is involved in osteosarcoma chemoresistance[J].Chinese Journal of Cancer,2016,35(7):366-373. 被引量:13
-
2胡硕,胡成平.医学细胞生物学——线粒体与细胞凋亡的研究进展[J].中国学术期刊文摘,2006,12(23):3-3.
-
3姜燕,张洁,张金阳.自噬与肿瘤耐药的研究进展[J].生命科学研究,2015,19(1):62-67. 被引量:3
-
4张海清.肿瘤耐药迷局[J].走近科学,2011(12):47-49.
-
5曾晓勇,杨为民,等.γ-谷氨酰半胱氨酸合成酶(γ-GCS)与肿瘤耐药[J].国外医学(分子生物学分册),2002,24(4):214-217. 被引量:3
-
6司鑫鑫,孙玉洁.DNA甲基化异常与肿瘤耐药[J].遗传,2014,36(5):411-419. 被引量:8
-
7Xiao-wei MA Yu-liang ZHAO Xing-jie LIANG.Nanodiamond delivery circumvents tumor resistance to doxorubicin[J].Acta Pharmacologica Sinica,2011,32(5):543-544. 被引量:2
-
8张海亮,唐圣松.细胞自噬与肿瘤耐药[J].中国生物化学与分子生物学报,2014,30(3):224-232. 被引量:11
-
9何明生,陈燕.热休克蛋白与肿瘤细胞耐药[J].中国实验血液学杂志,1998,6(3):178-181. 被引量:6
-
10刘军(综述),汪永红(综述),王昌富(审校).谷胱甘肽S-转移酶-π的生物学特性及其临床应用[J].国际检验医学杂志,2007,28(1):57-58. 被引量:14