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酰基辅酶A-胆固醇酰基转移酶抑制剂 被引量:1

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摘要 酰基辅酶 A-胆固醇酰基转移酶 ( ACAT)抑制剂可抑制体内小肠、肝脏及动脉的 ACAT,降低血浆总胆固醇及低密度脂蛋白胆固醇水平 ,同时阻止胆固醇酯化 ,减少胆固醇在动脉壁的蓄积 ,防止动脉粥样硬化的形成及发展。近年来 ACAT抑制剂具有很大发展潜力 ,可望成为一种新型的降血脂及抗动脉粥样硬化药。
出处 《国外医学(药学分册)》 2000年第4期231-233,共3页 Foreign Medical Sciences(Section of Pharmarcy)
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