高渗盐水联合特布他林雾化吸入佐治毛细支气管炎疗效观察

The clinical observation of hypertonic suline and terbutaline treatment of bronchiolitis

目的观察高渗盐水联合特布他林氧驱雾化吸入佐治毛细支气管炎的疗效。方法 102例患儿随机分为观察组48例,对照组54例。在两组给予相同的综合治疗基础上,观察组给予3%氯化钠3 ml+特布他林1 ml雾化吸入,对照组给予0.9%氯化钠2 ml+布地奈德1 ml+特布他林1 ml雾化吸入。观察2组疗效、症状、体征、住院时间及不良反应。结果观察组显效率为91.7%高于对照组77.8%,差异有统计学意义(P<0.05);住院天数、不良反应均少于对照组,差异有统计学意义(P<0.05)。结论氧驱雾化吸入3%氯化钠3 ml+特布他林1 ml治疗毛细支气管炎疗效优于0.9%氯化钠2 ml+布地奈德1 ml+特布他林1 ml雾化吸入,值得临床推广。

Objective To observe the efficacy of bronchiolitis treated with aerosol inhalation of hyper- tonic saline and terbutaline for adjutant treatment. Methods 102 cases were randomly divided into observation group of 48 and control group of 54. Both groups were given comprehensive treatment by the same way. The ob- servation group was given aerosol inhalation of hypertonic saline and terbutaline, while the control group was given aerosol inhalation of normal saline and terbutaline and budesonid. Observed 2 groups＇efficacy, lasting time of symptoms and signs, and length of stay, and adverse reaction. Results The total effective rate of the observa- tion group was 91.7 % higher than 77. 8 % of the control group, and the difference was statistically significant （P 〈 0. 05 ）. The extinction time of wheezing and cough was shorter than that of the control group, so was the length of stay, and the differences were statistically significant（ P 〈 0. 05 ）. Conclusion Treating bronchiolitis in chil- dren with aerosol inhalation of hypertonic saline and terbutaline for adjutant treatment has remarkablely better ef- ficacy than normal saline and terbutalins and budesonid, which is worth clinical popularizing and application.