十堰市16348例孕产妇4种传染性疾病检测结果分析

Analysis of results of four communicable diseases on 16 348 cases of pregnant women in Shiyan city

目的:了解本地区孕产妇对乙型肝炎、丙型肝炎、梅毒、艾滋病等4种传染性疾病的感染情况。方法:住院分娩的待产孕妇及门诊孕检者16348例分别进行乙型肝炎病毒血清标志物(HBVM)、丙型肝炎病毒抗体(抗HCV)、人类免疫缺陷病毒抗体(抗HIV)和梅毒抗体检测。结果:16348例孕产妇中发现血清乙型肝炎表面抗原(HBsAg)阳性1372例(8.39%),抗HCV阳性17例(0.10%),梅毒阳性(RPR及TPPA)333例(2.04%),抗HIV阳性2例。本地区孕产妇乙型肝炎感染率在逐年上升,2010年和2011年与2009年比较差异均无统计学意义(P>0.05);丙型肝炎感染率较低并呈逐年下降的趋势;梅毒的感染率在逐年上升,由2009年的1.59%上升至2011年的2.34%,2010年与2009年比较,差异无统计学意义(P>0.05),2011年与2009年比较差异有统计学意义(P<0.01)。结论:孕产妇是血源性疾病垂直传播的重要因素,对孕产妇人群应该高度重视,以减少血源性疾病通过母婴垂直传播感染,孕妇产前检查HIV、HBV、HCV及梅毒4项传染指标并及时采取干预措施,对优生优育具有重要意义。

Objective：To investigate the infection situation of the four communicable diseases hepatitis B,hepatitis C,syphilis and AIDS among pregnant women in this area.Method：16 348predelivery pregnant women received the pregnancy testing,including hepatitis B virus serum markers（HBVM）,anti-hepatitis C virus antibody（anti-HCV）,human immunodeficiency virus antibody（anti-HIV）and syphilis antibody.Result：There were 1372（8.39%）women hepatitis B virus surface antigen（HBsAg）-positive,17（0.1%）women anti-HCV positive,333（2.04%）syphilis-positive（RPR and TPPA）and 2anti-HIV positive in 16348pregnant women.The infectious incidence of hepatitis B was rising year after year.There was no significant difference between 2010,2011and 2009（P〉0.05）.The Infectious incidence of hepatitis C was low and dropping year by year.The infectious incidence of syphilis was rising from 1.59%in 2009to 2.34%in 2011,there was no statistic significance between 2009and 2010（P〉0.05）,and there was a significant difference between 2011and 2009（P〈0.01）.Conclusion：Pregnant woman is the important factor of vertical transmission of blood-borne diseases.It＇s should pay highly attention to the group of pregnant women to reduce vertical transmission of blood-borne diseases.There may be a great significance for healthy pregnant women to do antenatal examination of HIV,HBV,HCV and syphilis,and take intervening measures in time.