冬病夏治消喘膏穴位贴敷疗法预防儿童哮喘复发的临床研究

Clinical study on prevention of recurrence of asthma in children by Xiaochuangao acupoint paste:treating winter diseases in summer

目的:验证冬病夏治消喘膏穴位贴敷疗法治疗缓解期儿童哮喘的临床疗效。方法:将90例哮喘患儿随机分为3组,分别予冬病夏治消喘膏贴敷、吸入激素和冬病夏治消喘膏贴敷联合吸入激素治疗,随访1年。观察哮喘的复发情况及肺功能水平。结果:Ⅰ组(冬病夏治治疗组)预防哮喘复发的总有效率为63.3%稍低于Ⅱ组(激素治疗组)69.2%,但无统计学差异,Ⅲ组(冬病夏治联合激素治疗组)总有效率93.1%高于Ⅰ组和Ⅱ组,差异有统计学意义(P<0.05)。治疗前3组FEV1,FEV1/FVC及PEF比较,无明显差异;3组治疗后与治疗前比较,FEV1,FEV1/FVC,PEF均明显上升,差异有统计学意义(P<0.05);治疗后Ⅲ组与Ⅰ组及Ⅱ组FEV1,FEV1/FVC,PEF比较差异有统计学意义(P<0.05)。结论:冬病夏治消喘膏穴位贴敷治疗有预防哮喘复发的作用,与吸入激素联合治疗,效果更佳。

Objective： To verify the clinical efficacy of Xiaochuangao acupoint paste （XAP） in treating asthma in children. Method： Ninety children patients with asthma were randomly assigned to three groups with 30 patients each, being treated with XAP, hormone and XAP combined with hormone, respectively. The changes of the lung function and the recurrence times during one-year follow-up were observed. Result： Group Ⅱ（Hormone group） saw higher total effective rate （69.2%） than Group Ⅰ（XAP group）（63.3%）, but with no statistic difference between these two groups. Group Ⅲ （XAP and Hormone） saw the highest total effective rate （93.1%）, with significant statistic difference from the other two groups （P〈0.05）. All three groups saw the significant increase of the levels of FEV1, FEV1/FVC and PEF after the treatments（P〈0.05）, while no statistical difference of FEV1, FEV1/FVC, PEF were observed in the three groups before the treatments. After the treatments, statistic differences of FEV1, FEV1/FVC, PEF between Group Ⅲ and Group Ⅱ were observed （P〈0.05）. Conclusion： XAP played a role in preventing the recurrence of asthma in children. Combined with hormone, XAP showed better effects.