论道地药材品质辨识及其与生态环境的相关性研究策略

Strategy for research on quality identification and ecological environment-related of Dao-di herb

长期以来,道地药材品质评价缺少客观明确的方法和标准,使得道地药材"道地难辨";道地性与环境的相关性研究常因缺少客观品质指征而陷入"有目标,无指标"及"循环论证"的怪圈,难以揭示道地药材品质形成的生态环境因子。作者提出以道地药材品质评价方法和标准为突破口,从效入手,以效定质,以质论环,建立以"效-质-环"为研究路径的中药材道地性评价(道地药材品质生态学研究)思路和模式,以期为揭示影响道地药材品质形成的生态环境主导因子;建立道地药材临床合理应用剂量换算机制;阐明中药材道地性的现代科学内涵,解决制约道地药材生产发展与临床应用的关键问题提供研究基础。

For a long time, due to the shortage of a objective and clear method and standard for the quality evaluation of the Dao-di herb, it is difficult to distinguish the Dao-di herb. Geo-herbalism and environment-related studies often fall into the vicious circle of ＂have target but no indicators＂ and ＂circular reasoning＂ because of lack of objective and a clear indication of the quality characteristics. So it is difficult to reveal the ecological environment factors that form the quality of Dao-di herb. The research team put forward innovative idea that taking the medicine quality evaluation method and authentic standard as a breakthrough, starting from the effect, evaluating quality by effect, evaluating the environment by the drug quality, and establishing the thinking and pattern of identify authentic Chinese herbs （quality ecological studies of the Dao-di herb） based on the research path of ＂effect-quality-environment＂. The authors hope that they can provide theoretical and technical support to reveal the dominant factors of the ecological environment that impact of the quality of the Dao-di herb, build the Dao-di herb clinical application of dose conversion mechanism, clarify the connotations of the modern science of the Dao-di herb and solve the key issues that constraint the development of the Dao-di herb production and clinical application of it.