CEA、CA-50检测对良恶性胸水诊断价值探讨

A study on the CEA, CA-50 for the differential diagnosis of Benign and Malignant Hydrothorax

目的寻找简便有效的方法对良恶性胸水进行鉴别诊断。方法采用放射免疫分析技术对健康对照组 30例、已确诊的恶性胸水组 15例、良性胸水组 33例血清及胸水进行CEA、CA 5 0平行对照检测。结果恶性胸水组血清及胸水CEA、CA 5 0水平显著高于良性胸水组。结论提示对胸水进行CEA、CA 5 0检测有利于良恶性胸水鉴别诊断 ,且CEA、CA 5 0联合检测可提高恶性胸水诊断阳性率。

Objective To search an easy and effective method for the differential diagnosis between benign and malignant hyolrothorax. Methods The radioimmunoassay technique was used. The CA 50 and CEA level of serum and hydrothorax of 15 patients with malignant hydrothorax, 33 patients with benign hydrothorax, and 30 healthy persons as the control were determined by RIA. Results The CA 50 and CEA level of serum and hydrothorax in malignant hydrothorax were significant higher than those in benign hydrothorax( P <0 01) Conclusion It suggested that the hydrothorax CA 50 and CEA determination was effective for the differential diagnosis between benign and malignant hydrothoraxes. The positive diagnostic rate of malignant hydrothorax was increased when the combined determination of CA 50 and CEA.