两栖类动物抗菌肽对病原微生物作用研究进展

Advances in the research of the function of amphibian antimicrobial peptides against pathogenic organisms

两栖动物抗菌肽是体内经诱导产生的1种对抗外源性致病菌作用的防御性小分子多肽,是机体免疫系统的重要成分,是构成防御病源微生物入侵的第一道屏障。对两栖类动物皮肤抗菌肽的种类、功能、在两栖类中的作用及其应用进行了阐述。

Amphibian antimicrobial peptides （AMPs） are small defensive peptides to pathogens in organisms after inducting. AMPs form the first line of host defense against pathogenic infections, and they are key components of the innate immune system of amphibian. The review focused on the classification, function, application of amphibian antimicrobial peptides and how important were skin antimierobial peptides in protecting the organism against pathogens encountered.