期刊文献+

2011年包头市320例射线接触人员染色体畸变情况分析 被引量:1

Chromosomal Aberrations Analysis on 320 occupationaly radiation exposed workers of Baotou City in 2011
下载PDF
导出
摘要 目的对射线接触人员进行细胞遗传学监测,为我市射线工作人员的健康监护提供科学依据。方法对包头市2011年旗、县、区级医院及相关单位部分进行放射治疗、从事X线工作、工业探伤、医用同位素的320名射线接触人员和60名非射线接触人员,采用微量全血培养法进行外周血淋巴细胞染色体畸变检测。结果从事放射治疗、医用X线、工业探伤、医用同位素的工作人员染色体畸变率分别为0.357%、0.325%、0.318%、0.306%,均明显高于对照组(0.043%),经统计学处理有统计学差异(P<0.01),其中放射工龄5~14年组高于其它3组(P<0.05),放射工龄25~36年低于其它3组(P<0.05)。结论不同射线对接触人群的健康均具有一定的辐射损伤效应,应加强射线接触人员的辐射防护工作。 Objective Observations of cell genetic toxic effects in occupation population, supply scientific basis of defendence from radiation. Methods 320 X-ray workers exposed to radiation in 2011 were selected as cases and 60 workers without X-ray exposed as controls. The workers were divided into groups according to the length of radiation service and type of radiation work. Chromosome were examined using the whole blood of tiny culture method. Results The chromosome aberration rates in the exposed workers of radiation treatment (0.357%), nuclear medicine group (0.306%), industrial X-ray detection group (0.318%), and medical X -ray detection group (0.325%) were higher than that of the control group (0.043%), each of which had significant difference. Compared with the length of service, aberration rate was highest in the workers served 5-14 years group and lowest in group of 25-36 years. The chromosome aberration rate has relationship with work ages and radiological species. Conclusion Occupationally exposed to radiation makes harmful effects on workers. It is necessary to enhance the denfensive measurements in radiological work and take more effective protections to improve the work's health.
出处 《疾病监测与控制》 2012年第8期465-466,共2页 Journal of Diseases Monitor and Control
关键词 电离辐射 细胞遗传学 染色体畸变 Ionization radiation Cytogenetics Chromosome distortion
  • 相关文献

参考文献4

二级参考文献18

  • 1严宗佑,王毅,乌丽娅,李瑞雪.新疆放射工作人员细胞遗传学分析及剂量──效应关系研究[J].中华放射医学与防护杂志,1994,14(5):325-328. 被引量:9
  • 2染色体专题组.我国医用诊断X线工作者的染色体畸变分析[J].中华放射医学与防护杂志,1984,4(5):46-46.
  • 3金璀珍主编.放射生物剂量估量[M].北京:军事医学科学出版社,2002.47-8.
  • 4Fenech M Morley AA. Measurement of micronucleis in lymphocytes. Murat Res,1985;147(1-2):29-36.
  • 5Barquinero JF, Barrios L, Caballin MR et al. Cytogentic analysis of lymphcytes from hospital workers--occupationally exposed to low levels of ionizing radiation. Murat Res, 1993;286(2):275-9.
  • 6Balakrishnan S, Rao SB. Cytogenetic analysis of peripheral blood lymphocytes of occupational workers exposed to low levels of ionizing radiation. Murat Res,1999;442(1):37-42.
  • 7Vijayalaxmi, Leal BZ, Deahl TS et al. Variability in adaptive response to low dose radiation in human blood lymphocytes:consistent results from chromosome aberrations and micronuclei. Murat Res,1995;348(1):45-50.
  • 8Darroudi F, Natarajan AT, Bentvelzen PAJ et al. Detection of total and partial-body irradiation in a monkey model:a comparative study of chromosome aberration, micronucleus and premature chromosome condensation assays. Int J Radiat Biol, 1998;74(2) :207-15.
  • 9Savage JRK. A comment on the quantitative relationship between micronuclei and chromosome aberrations. Mutat Res,1988;207(1) :33-6.
  • 10Keshava C, Ong T, Nath J. Comparative studies on radiation-induced micronuclei and chromosome aberrations in V79 cells.Mutat Res, 1995;328(1) :1-9.

共引文献30

同被引文献8

  • 1LONNERDAL B. Bioactive proteins in breast milk [ J 1. J Paediatr Child Health ,2013 ,g9 ( Suppl 1 ) : 1 - 7.
  • 2GEORGIEVA S, POPOV B, BONEV G. Radioprotective effect of Haberlea rhodopensis ( Friv. ) leaf extract on gamma-radiation-in- duced DNA damage, lipid peroxidation and antioxidant levels in rabbit blood[ J]. Indian J Exp Biol,2013,51 ( 1 ) :29 -36.
  • 3SABERI A, SALARI E, LATIFI S M. Cytogenetic analysis in lym- phocytes from radiation workers exposed to low level of ionizing radia- tion in radiotherapy, CT-scan and angiocardiography units [ J ]. Mutat Res,2013,750(1/2) :92 -95.
  • 4GONZ:tLEZ-CH:VEZ S A, ARI:VALO-GALLEGOS S, RASCON- CRUZ Q. Laetoferrin: structure, function and applications[J:. Int J Antimierob Agents, 2009,33 (4) :301, el - 8.
  • 5IVANOV A A, ULANOVA A M, STAVRAKOVA N M, et al. Anti- radiation effect of lactoferrin [ J ]. Radiats Biol Radioecol, 2009, 49 (4) : 456 -461.
  • 6姜红,方仁丽,李舟,布敬双.贵州省放射工作人员外周血淋细胞染色体畸变率及微核率分析[J].中国辐射卫生,2012,21(1):50-52. 被引量:8
  • 7贺磊,金百翰,倪啸晓,刘吉元,王方辉,徐伟刚.高压氧预处理通过热休克蛋白70降低大鼠减压病患病情况观察[J].中国职业医学,2012,39(2):150-152. 被引量:2
  • 8魏超,邓大平,邵传静,侯殿俊,李福生,乔建维,封丽.人乳铁蛋白对小鼠急性辐射损伤影响[J].中国职业医学,2012,39(5):384-386. 被引量:1

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部