摘要
针对赖氨酸发酵过程非线性、大滞后、多变量动态耦合,关键生化参数难以实时在线测量等问题,提出一种改进的粒子群-支持向量机(PSO-SVM)逆发酵过程软测量建模方法。首先分析逆系统的存在性,并结合赖氨酸发酵过程,引入发酵特征信息和舍弃次要信息构造逆扩展模型;然后利用支持向量机离线辨识初始逆扩展模型,并根据系统输入与模型输出的偏差信号,采用粒子群算法对初始逆扩展模型进行在线校正;最后将校正后的逆扩展模型串联在原发酵过程之后构成复合伪线性系统,实现不直接可测关键生化参数的在线预测。以L-赖氨酸流加发酵过程为例,验证了所提算法能够对发酵过程关键生物量参数进行较准确的在线预测,较普通的SVM逆建模方法具有更高的预测精度。
Lysine fermentation process,which is characterized by nonlinear,large time-delay,multivariable dynamic coupling,is very difficult to realize crucial biochemical parameters on-line measurement.A soft-sensing modeling method was proposed based on PSO-SVM inversion theory.Firstly,the reversibility of the system was analyzed and the inverse extension model was built by introducing the feature information and abandoning the secondary information,and the inverse extension model was built offline with SVM which had good fitting capability and was adjusted online by PSO based on the error information between actual fermentation process input and model output.Finally,the inverse extension model was applied to the fed-batch L-lysine fermentation process and prediction with on-line soft-sensor of the directly immeasurable crucial biochemical parameters was realized.The simulations showed that the crucial biochemical parameters could be predicted.The results also showed that the proposed method was more accurate compared with the alternative modeling methods.
出处
《化工学报》
EI
CAS
CSCD
北大核心
2012年第9期3000-3007,共8页
CIESC Journal
基金
国家高技术研究发展计划项目(2011AA09070301
2007AA04Z179)
江苏省自然科学基金项目(BK2011465)~~