全胚冷冻预防卵巢过度刺激综合征42例分析

Analysis on 42 cases with whole embryo frozen for prevention of ovarian hyperstimulation syndrome

目的:研究全胚冷冻预防卵巢过度刺激综合征(OHSS)的临床疗效。方法:42例行体外受精-胚胎移植助孕的患者因有OHSS的风险取消新鲜胚胎移植,进行全胚胎冷冻,3个月后进行共59周期的冷冻胚胎移植,统计其临床资料。结果:42例患者有3例发生中、重度OHSS,发生率为7.10%,冷冻胚胎妊娠率为40.54%,累积妊娠率为58.57%,双胎妊娠率为25.78%。结论:全胚冷冻是预防OHSS并取得良好临床效果的有效方法。

Objective： To research the clinical effect of whole embryo frozen for prevention of ovarian hyperstimulation syndrome （OHSS） . Methods： A total of 42 patients receiving IVF-ET canceled fresh embryo transfer because of risk of OHSS, so they received whole embryo frozen, a total of 59 cycles of frozen embryo transfer were obtained after three months, then the clinical data were analyzed statistically. Results ： Among 42 patients, three patients were found with moderate to severe OHSS, the incidence of OHSS was 7. 10% , the pregnancy rate of frozen embryo was 40. 54% , the cumulative pregnancy rate was 58.57% , and the rate of twin pregnancy was 25.78%. Conclusion： Whole embryo frozen is an effective method to prevent OHSS and achieve good clinical effect.