老年慢性心衰证候分型与NT-proBNP相关性的临床研究

Clinical Observation On the Relationship Between Symptomatic Classification Of TCM and NT-proBNP In Elderly Patients With Chronic Heart Failure

目的:观察老年慢性心衰患者证侯分型与NT-proBNP的相关性。方法:选择100例老年慢性心衰患者,按照中医辨证分为气阴两亏(25例)、气虚血瘀(60例)、阳虚水泛(15例)3组。另取老年健康者40例作为对照,比较慢性心衰各组及健康者NT-proBNP有无差异。结果:NT-proBNP数值在慢性心衰各组中按照阳虚水泛证>气虚血瘀证>气阴两亏证递减,慢性心衰各组间NT-proBNP较健康对照组均有统计学意义(P<0.01)。结论:NT-proBNP与慢性心衰各证型之间有一定的相关性,可结合临床参考辨证。

Objective：To observe the relationship between symptomatic classification of TCM and NT-proBNP in elderly patients with chronic heart failure. Methods： Chose 100 elderly patients with chronic heart failure, and derided info 3 groups： deficiency of qi and yin group （25） , qi deficiency and blood stasis group （60） , yang deficiency and water overflowing group （15）. Chose 40 healthy people as the control group. Compared the level of NT-proBNP in 4 grollps. Results ： The level of NT-proBNP sorted in descending order ： the yang deficiency and water overflowing group 〉 the qi deficiency and blood stasis group 〉 deficiency of qi and yin group. Compared with the healthy people , the level of NT-proBNP in CHF patients of all types of showing significant difference, P 〈 0. 01. Conclusion：There is certain correlation between syndrome differentiation type of TCM and NT-proBNP in elderly patients with CHF. The type of TCM can be made sure through the level of NT-proBNP combining with symptom.