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Micro-RNA在骨关节炎中的研究进展 被引量:6

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摘要 骨关节炎(osteoarthritis,OA)是由全身易感因素和局部机械性因素相互作用导致的一种以关节软骨退变为主的常见老年性骨与关节退行性疾病。其主要的临床表现为:受累关节的疼痛、肿胀、畸形、活动受限,影像学的主要表现为:受累关节的关节间隙变窄、软骨下骨周围骨赘形成。
出处 《中国矫形外科杂志》 CAS CSCD 北大核心 2012年第17期1600-1603,共4页 Orthopedic Journal of China
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参考文献49

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同被引文献78

  • 1王维山,史晨辉,何仁豪,周圆家,陈安民,郭风劲.MicroRNAs、uPA及MMP-3在骨关节炎患者滑膜组织中的表达及相关性[J].中国老年学杂志,2014,34(4):871-873. 被引量:5
  • 2王维山,史晨辉,周卓浩,王永明,董金波,刘维钢,何斌,管兴发.一侧兔膝关节注射外源性尿激酶型纤溶酶原激活物引起双侧膝关节软骨降解的实验[J].中国组织工程研究与临床康复,2007,11(19):3738-3741. 被引量:16
  • 3骨关节炎诊治指南(2007年版)[J].中华骨科杂志,2007,27(10):793-796. 被引量:1962
  • 4Kimura T. Progress of research for osteoarthritis, an overview of the recent knowledge on osteoarthritis:pathogenesis, evaluation and therapies [J ]. Clin Calcium, 2009, 19 ( 11 ): 1565-1571.
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  • 7Hosono K, Nishida Y, Knudson W, et al. Hyaluronan oligosa- ccharides inhibit tumorigenicity of osteosareoma cell lines MG- 63 and LM-8 in vitro and in vivn via perturbation of hyaluronan- rich pericellular matrix of the cells [J]. Am J Pathol, 2007, 171 (1): 274-286.
  • 8Brun P, Panfilo S, Daga Gordini D, et al. The effect of hyaluronan on CD44-mediated survival of normal and hydroxyl radical-danlaged chondrocytes [J]. Osteoarthritis Cartilage, 2003, 11 (3): 208-216.
  • 9Linh T. T. Le,Tracey E. Swingler,Ian M. Clark.Review: The Role of MicroRNAs in Osteoarthritis and Chondrogenesis[J]. Arthritis & Rheumatism . 2013 (8)
  • 10L. Zhang,M. Yang,P. Marks,L.M. White,M. Hurtig,Q.-S. Mi,G. Divine,G. Gibson.Serum non-coding RNAs as biomarkers for osteoarthritis progression after ACL injury[J]. Osteoarthritis and Cartilage . 2012 (12)

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