颅脑损伤后肠内外营养支持的对比分析

Traumatic Brain Injury and Enteral Nutrition Support of Comparative Analysis

目的对比分析颅脑损伤后(2～14 d)肠外营养(TPN)与肠内营养(EN)+肠外营养(TPN)联合治疗的优势。方法将30例颅脑损伤患者(GCS≤9分)随机分成两组,早期分别给予TPN与EN+TPN联合治疗,在摄入同等热量及等量蛋白质的条件下进行对比分析。结果 EN+PN联合组24 h排除氮明显少于TPN组,氮平衡、肌酐指数(ICr)等营养指标优于TPN组。结论 EN+TPN联合治疗可有效促进颅脑损伤后由于下丘脑植物神经功能紊乱所致的胃肠抑制功能的恢复,胃肠蠕动功能的恢复,减少损伤性肠麻痹发生率,充分保护胃黏膜。有效缓解颅脑损伤后的机体高代谢所致的营养不足,促进意识状态的恢复。

Objective Comparative analysis of craniocerebral injury（2~14 d）parenteral nutrition（TPN）and enteral nutrition（EN）and parenteral nutrition（TPN）combined therapeutic advantage.Methods The 30 cases of patients with brain injury（GCS≤ 9）were randomly divided into two groups,early were given TPN and EN＋TPN combined treatment,in the same heat and amount of protein intake condition carries on the contrast analysis.Results EN＋TPN joint group of 24 h to exclude nitrogen was obviously less than group TPN,nitrogen balance,creatinine index（ICr）and other nutritional index was better than TPN group.Conclusion EN＋TPN combined therapy can effectively promote after head injury due to hypothalamic plant nerve function disorder induced by inhibition of the gastrointestinal function recovery,gastrointestinal peristaltic function recovery,reduce the damage of intestinal paralysis occurring rate,full protection of gastric mucosa.Effective to alleviate the high metabolism after head injury caused by inadequate nutrition,promote the recovery of consciousness.