三维彩色多普勒超声对慢性肾炎肾血流灌注观察的意义

The Significance of Observation by Three-Dimension Colorful Doppler Ultrasonic over the Renal Blood Flow Perfusion of chronic nephritis

目的通过三维彩色多普勒超声定量分析肾内血流的灌注参数和肾功能测值的关系，了解慢性肾炎患者肾脏损害的程度。方法根据美国肾脏疾病生存质量指导（K／DOQI）诊断及分期标准选择慢性肾炎患者60例，与正常对照组30例进行比较，应用三维彩色多普勒超声，观察肾脏形态结构，并利用血流分析技术观察肾脏的血流灌注，计算血管指数、血流指数。将肾血流灌注参数与肾功能测值及肾活检病理结果进行对照。结果慢性。肾炎组与正常对照组比较存在显著差异（P〈0．05），并随着肾功能损害越严重，差异越显著。结论三维彩色多普勒超声对慢性肾炎各期肾血流灌注观察，可以监测慢性肾炎患者的。肾损害程度。

Objective The Three-Dimension Colorful Doppler Ultrasonic was adopted to analyze quantitatively the relationship between the perfusion indices of blood flow inside the kidney and the measured values of kidney function so as to know the degree of the kidney damage of chronic nephritis patients. Methods 60 cases of chronic nephritis were involved in the study group according to the di- agnosis and staging criteria of Kidney Disease Survival Quality Instruction made by NKF （K/DOQI） compared with 30 cases as the normal control group. The Three-Dimension Colorful Doppler Ultrason- ic was adopted to observe the morphology and structure of kidney and the blood perfusion of kidney was observed by blood flow analysis technology. The vessel index （VI） and flow index （FI） were also calculated. The kidney blood perfusion indices were compared with the measured values of kidney function and the biopsy pathology results. Results The significant difference existed between the chronic nephritis study group and normal control group （P^0. 05） while it became more and more ap- parent as the kidney function was injured more and more severely. Conclusions The Three-Dimension Colorful Doppler Ultrasonic can observe the kidney blood perfusion at various stages of chronic nephri- tis so that it can monitor the degree of kidney damage of chronic nephritis.