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自由基清除剂依达拉奉在预防一氧化碳中毒迟发性脑的临床观察 被引量：3

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摘要 在我国北方,冬季取暖以煤炭为主,因此煤炭的不完全燃烧所产生的急性一氧化碳（CO）中毒事件时有发生。急性CO中毒患者经过及时治疗,约有10%～30%的患者于急性中毒回复后,经过3～24天的＂假愈期＂可再次出现一系列神经精神症状,称之为＂CO中毒迟发性脑病＂（delayed encephelopothy after carbon monoxide poisoning，DEACMP）。
作者 杨立波 苏国华 米玉霞 艾明华 刘立海 刘深龙 陈慧丽 张海燕 刘友刚
机构地区 沧州市人民医院神经内科 吉林省博大制药有限责任公司北京联络处
出处 《临床荟萃》 CAS 2012年第17期1532-1533,共2页 Clinical Focus
关键词 一氧化碳中毒 缺氧缺血 脑 高压氧 依达拉奉
分类号 R749.63 [医药卫生—神经病学与精神病学]
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参考文献7

  • 1Ernst A,Zibrak JD. Carbon monoxide poisoning[J].New Engl JMed, 1998,339(22) : 1603-1608.
  • 2OterS, Topal T, Sadir S, et al. Oxidative stress levels in rats following exposure to oxygen at 3 arm for 0-120 min[J]. Aviat Space Eniron Med,2007,78(12) : 1108-1113.
  • 3Nemoto EM, Betterman K. Basic physiology of hyperbaric oxygen in brain[J]. Neurol Res,2007,29(2) : 116-126.
  • 4Wang P, Zeng T, Zhang CL, et al. Lipid peroxidation was involved in the memory impairment of carbon monoxide-induced delayed neuron damage [J]. Neurochem Res, 2009, 34 (7) : 1293 1298.
  • 5Mannaioni PF, Vannacci A, Masini E, et al. Carbon monoxide: the bad and the good side of the coin, from neuronal death to anti-inflammatory activity[J]. Inflamm Res, 2006,55 ( 7 ) : 261- 273.
  • 6Piantadosi CA,Tatro L,Zhang J. Hydroxyl radical production in the brain after CO hypoxia in rats[J]. Free Radie Biol Med, 1995,18 (3) :603-609.
  • 7Kaur C, Ling EA. Antioxidants and neuroprotection in the adult and developing central nervous system[J]. Curr Med Chem, 2008,15(29) :3068-3080.

同被引文献38

  • 1马烈,孙斌.依达拉奉治疗血管源性帕金森综合征的疗效观察[J].中国全科医学,2008,11(19):1794-1795. 被引量：19
  • 2Edaravone Acute Infarction Study Group. Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters[J]. Cerebrovasc Dis, 2003, 15 (3): 222-229.
  • 3Mizuno A, Umemura K, Nakashima M. Inhibitory effect of MCI-186, a free radical scavenger, on cerebral ischemia following rat middle cerebral artery occlusion [J]. Gen Phamracol, 1998, 30 (4): 575-578.
  • 4Zhang N, Komine-Kobayashi M, Tanaka R, et al. Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal is chemia in mice brain[J] . Stroke, 2005, 36 (10) : 2220-2225.
  • 5Yang J, Liu M, Zhou J, et al. Edaravone for acute intracerebral haemorrhage [J]. Cochrane Database Syst Rev, 2011, 16 (2): CD007755.
  • 6Peeling J, Yan H J, Chen SG, et al. Protective effect of free radical inhibitors in intracerebral hemorrhage in rat [J]. Brain Res, 1998, 795 (2) : 63-70.
  • 7Yan Y, Gong K, Ma T, et al. Protective effect of edaravone against Alzheimer's disease-relevant insults in neuroblastoma N2a cells[J]. Neurosci Let-t, 2012, 531 (2) : 160-165.
  • 8Bouma GJ, Muizelaar JP, Choi SC, et al. Cerebral circulation and metabolism after severe traumatic brain injury: the elusive role of ischemia[J]. J Neurosurg, 1991, 75 (5) : 685-693.
  • 9Bakey KA, Sweeney KM, Wood JH. Pathophysiology of cerebrospinal fluid in head injury: part 1: pathological changes in cerebrospinal fluid solute after traumatic injury [J]. Neurosurgery, 1986, 18 (2): 234-243.
  • 10Ohta M, Higashi Y, Yawata T, et al. Attenuation of axonal injury and oxidative stress by edaravone protects against cognitive impairments after traumatic brain injury [J]. Brain Res, 2013, 1490(1): 184-192.

引证文献3

二级引证文献7

临床荟萃
2012年 第17期

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