摘要
目的:探讨贫血对慢性心力衰竭患者血浆氮末端—前体脑钠肽(NT-proBNP)、羧基端活性段脑钠肽(BNP)的影响。方法:研究对象为76例因心功能不全入院的慢性心力衰竭患者,其中31例贫血。测定血浆NT-proBNP、BNP、血常规、肾功能等。结果:1)两组NT-proBNP比较差别没有统计学意义(P>0.05)。但是,BNP在两组中差别有统计学意义(P<0.05)。2)相关性分析示血红蛋白浓度与BNP呈现负相关(r=-0.687),与NT-proBNP无关。结论:研究表明在评价心力衰竭患者NT-proBNP、BNP水平时需考虑其贫血等相关影响因素。
Objective：To study the influence of anaemia on BNP and NT - proBNP levels in a large group of hospitalised HF patients. Methods： 76 patients hospitalised for HF were studied. Of these patients, 31 were anaemic. BNP and NT -proBNP levels were measured in all patients before discharge. Blood routine test and renal function test were also carried out on these patients. Results ： 1. NT - proBNP levels had no difference in the patients with a- naemia and patients without anaemia （ P 〉 0.05 ）. BNP level of anaemia patients was signifcantly higher than that in patients without anaemia（ P 〈 0.05）. 2. Pearson analysis showed plasma haemoglobin level had negative correlation with the levels of BNP. Conclusion： These results indicate that anaemia should be taken into consideration during the interpretation of BNP and NT - proBNP levels in HF patients.
出处
《中国卫生检验杂志》
CAS
北大核心
2012年第8期1872-1874,共3页
Chinese Journal of Health Laboratory Technology
