2009年-2011年汉中市流感病毒核酸检测结果分析

Analysis of influenza virus nucleic acid detection results from 2009 to 2011 in Hanzhong city

目的:分析汉中市2009年-2011年流感病毒核酸检测结果,为流感的预防控制提供科学依据。方法:对国家级流感监测哨点医院送检的流感样病例鼻咽拭子标本采用Real-time RT-PCR方法进行检测。结果:共检测标本896份,检出流感病毒核酸阳性标本236份,总阳性率为26.34%。流感病毒的感染性无性别差异(P>0.05),有城乡差异(P<0.05),各年龄组阳性率有差异(P<0.05)。结论:汉中市2009年-2011年流感主要出现在冬春季,2009年11月-2010年1月、2011年1月-2011年2月以甲型H1N1流感病毒为优势毒株,2010年及2011年的3月-2011年4月以B型流感病毒为优势毒株,H3亚型流感病毒在9月至次年3月以散发的形式存在。

Objective：To analyze influenza virus nucleic acid test results from 2009 to 2011 in Hanzhong and provide a scientific basis for the flu prevention and control. Methods： Real - time RT - PCR method was used to detect nasopharyngeal swabs specimens selected from national influenza surveillance sentinel hospitals. Results： In total, 896 specimens were detected and 236 were positive for the influenza virus nucleic acid. The positive rate was 26.34%. Influenza virus infection was found no sex difference （P 〉0.05） but to have urban -rural differences （P 〈 0.05 ） , the positive rate of each age group had difference （ P 〈 0.05 ）. Conclusion ： In Hanzhong city, influenza was prevalent in winter and spring from 2009 to 2011. A（ H1N1 ） was the dominant strain from September 2009 to January 2010, and January 2011 to February 2011, influenza type B was the dominant strain in 2010 and March 2011 to April 2011, while influenza subtype H3 was the dominant strain from September to next March.