肾衰竭患者血清铁蛋白及甲状旁腺激素水平的变化

The changes of serum ferritin and parathyroid hormone in patients with renal failure

目的探讨血清铁蛋白(SF)及甲状旁腺激素(PTH)在急、慢性肾衰竭诊断及治疗中的临床意义。方法随机选取急性肾衰竭患者18例(A组)和慢性肾衰竭患者30例(B组),另选取30名健康体检者(对照组,C组),检测SF、PTH、血肌酐(Cr)及血尿素(BUN)水平。结果 A组SF水平明显高于B组和C组(P<0.01),B组与C组比较无统计学差异(P>0.05);B组PTH水平显著高于A组和C组(P<0.01),A组与C组比较无统计学差异(P>0.05)。结论急性肾衰竭患者的SF明显增高,慢性肾衰竭患者的SF水平无显著变化;慢性肾衰竭患者的血清PTH水平显著增高,急性肾衰竭患者的血清PTH水平无显著变化。

Objective To study the diagnosis and treatment value of serum ferritin（SF） and parathyroid hormone（PTH） in acute and chronic renal failure. Methods Randomly selected 18 patients with acute renal failure as ARF group（group A） and 30 patients with chronic renal failure as CRF group（group B）,while 30 healthy volunteers were selected as the control group（group C）.SF,PTH,Cr and BUN levels were detected. Results The SF levels of group A were significantly higher than that of group B and group C（P0.01）,while the levels of group B and group C had no significant difference（P0.05）;The PTH levels of group B were significantly higher than that of group A and group C（P0.01）,while the levels of group A and group C had no significant difference（P0.05）. Conclusion The SF level of ARF was significantly higher,while that of CRF had no significant change.The PTH level of CRF was significantly higher,while that of ARF had no significant change.