以呼吸衰竭为主要表现的甲状腺功能减退症临床分析

Clinic Analysis of Hypothyroidism with Respiratory Failure as the Main Symptom

目的提高临床医生对甲状腺功能减退症(甲减)并发急性呼吸衰竭的认识,减少误诊,提高救治率。方法对2002年11月-2011年6月收治的6例甲减并发急性呼吸衰竭患者予以有创机械通气及早期使用左旋甲状腺素治疗,使病症得以控制和治愈。结果患者使用有创机械通气治疗平均7 d,住院治疗14～43 d,平均(28.6±14.4)d,5例治愈,1例死亡。结论甲减并发呼吸衰竭早期使用机械通气及甲状腺激素替代治疗可提高抢救成功率。

Objective To promote clinical doctors＇ understanding of respiratory failure caused by hypothyroidism, reduce the rate of misdiagnosis, and increase the rate of cure. Methods We retrospectively analyzed the clinical data of six patients with respiratory failure caused by hypothyroidism in our hospital from November 2002 to January 2011. The patients were treated by invasive mechanical ventilation and levothyroxine. Results The invasive mechanical ventilation time averaged 7 days, and hospitalization period ranged from 14 to 43 days with an average time of （8.6 ~ 14.4） days. Five patients were completely cured and one died. Conclusion Early treatment with mechanical ventilation and levothyroxine can raise the curing rate of hypothyroidism combined with respiratory failure.