剥脱综合征性青光眼患者血清和房水中NO浓度的测定

Detection of nitric oxide concentration in serum and aqueous humor of peseudo-exfoliation glaucoma patients

目的:测定剥脱综合征性青光眼(peseudoexfoliation glaucoma,PEG)患者血清及房水一氧化氮(nitric oxide,NO)浓度,并探讨其在PEG发病中的作用。方法:应用硝酸还原酶法测定PEG患者(实验组)及白内障患者(对照组)血清及房水NO浓度。结果:实验组血清及房水NO浓度明显低于对照组(P<0.01)。结论:PEG患者血清及房水NO浓度降低,可能是导致房水滤过阻力增高的原因之一。

AIM：To measure the concentration of nitric oxide （NO） in serum and aqueous humor of the peseudoexfoliation glaucoma （PEG） patients and to study its possible role in the pathogenesis of PEG.METHODS：The NO concentration in serum and aqueous humor of PEG patients （experimental group） and cataract patients（control group） was detected by nitric acid reductase method.RESULTS：The NO level in serum and aqueous humorin experimental group were obviously lower than that of in control group （P0.01） .CONCLUSION：The decrease of NO concentration in serum and aqueous humor of PEG patients may be one of reasons of filtration resistomce increase.