摘要
[目的]研究黑骨藤提取物对H2O2诱导的PC12氧化损伤的保护作用。[方法]使用H2O2氧化压力诱导PC12出现氧化损伤,检测黑骨藤乙醇提取物对PC12细胞的保护作用。[结果]与模型对照组相比,黑骨藤乙醇提取物浓度在16~128μg/mL时,能显著提高PC12细胞的存活率,呈典型的量效关系。[结论]黑骨藤乙醇提取物具有抗氧化损伤作用。
[Objective] The aim was to study the protective effects of Periploca forrestii Schltr.root extract against cytotoxicity induced by hydrogen peroxide in PC12 cells.[Method] The model of PC12 cells toxicity induced by hydrogen peroxide was established and the protective effects of Periploca forrestii Schltr.root extract on PC12 cells were detected.[Result] Compared to negative control,Periploca forrestii Schltr.root extract could protect PC12 cells at concentration ranges of 16-128 ug/mL at a dose-response manner.[Conclusion] Periploca forrestii Schltr.root extract showed anti-oxidative effect on PC12 cells.
出处
《宁夏农林科技》
2012年第8期139-140,共2页
Journal of Ningxia Agriculture and Forestry Science and Technology
基金
贵州省教育厅自然科学类一般项目(2010[305])
关键词
黑骨藤
PC12细胞
抗氧化
Periploca forrestii Schltr.
PC12 cells
Anti-oxidative effect
