期刊文献+

皮肤转移性黑色素瘤1例

下载PDF
导出
摘要 1 临床资料 男性患者,53岁,因"皮肤恶性黑色素瘤术后5月,左小腿、左大腿丘疹1月"就诊.患者自幼左膝部外侧有一花生大小黑痣,5月前该痣渐渐增大,并同侧腹股沟淋巴结肿大,院外就诊病检确诊皮肤恶性黑色素瘤,于2011年5月行手术切除及同侧淋巴结清扫术.1月前于左小腿外上方及左大腿内上方出现红色丘疹,无瘙痒、疼痛等自觉症状,遂就诊.查体:左小腿外上方可见粟粒至豌豆大小的红色丘疹,质地硬,丛集性分布,左大腿内上方有类似皮疹.病检及免疫组化:表皮大致正常,肿瘤细胞位于真皮内,细胞异型,核仁明显,核分裂像多见,胞浆丰富,部分呈巢状排列.免疫组化:S-100(+),HMB45(+),CK(-).考虑皮肤转移性黑色素瘤.患者进一步行胸部、腹部CT及骨扫描,未见转移病灶.
出处 《皮肤病与性病》 2012年第4期242-243,共2页 Dermatology and Venereology
  • 相关文献

参考文献8

  • 1刘佳勇,方志伟,白楚杰,等.前哨淋巴结活检在皮肤恶性黑色素瘤诊治中的初步应用[C].2009年首届全国中西医肿瘤博士及中青年医师论坛,312.
  • 2滕胜,宋金纲,张如明,杨蕴,马育林.85例皮肤恶性黑色素瘤手术治疗分析[J].中国肿瘤临床,2003,30(6):403-405. 被引量:4
  • 3Bishop JN, BatailleV, GavinA, et al. The prevention, diagnosis, re-ferral and management of melanoma of the skin: concise guidelines [J], Clin Med, 2007, 7 (3) : 283-290.
  • 4Weyandt GH, Eggert AO, Houf M, et al. Anorectal melanoma: sur- gical management guidelines according to tumoklr thickness [ J], Br J cancer, 2003, 89 ( 11 ) : 2019-2022.
  • 5LavieA, Desouches C, Casanova D, et al. Surgical management of cutaneous malignant melanoma [J]. Ann Chir Plast Esthet, 2007, 52 (1): 1-13.
  • 6Morton DL, Thompson JF, Cochran AJ, et al. Sentinel-node biopsy or nodal observation in melanoma [J]. New Engl J Med, 2006, 355 (13): 1307-1317.
  • 7Lock-Andersen J, Horn J, Sjostrand H. Prognosis 'after sentinel node biopsy in malignant melanoma [J].Ugeskr Laeger, 2006, 168 (25) : 2457-2462.
  • 8Uhner A, Melzger S, Fierlbeek G. Sneeessful palliation of stenosing anoreetal melanoma by intratum oral injections with natural interferon -beta [J]. melanoma Res, 2002, 12 (4) : 395-398.

二级参考文献10

  • 1[1]Anbari KK, Schuchter LM, Bucky LP. Melanoma of unknown primary site. Presentation, treatment and prognosis-a single institution study[J]. Cancer, 1997, 79:1816
  • 2[2]Day CL, Harrist TJ, Gorstein F, et al. Malignant melanoma:prognostic significance of ″microscopic satellites″ in the reticular and subcutaneous fat[J]. Ann Surg, 1981, 194:108
  • 3[3]Harris MN, Roses DF. Malignant melanoma: treatment.Friedman RJ, Rigel DS, Kopt AW, et al. Cancer of the skin [M]. W.B.Saunder Company. Harcourt Brace Jovanorich. Ine.Philadelphia, 1991,177~197
  • 4[4]Ringborg U, Andersson R, Eldh J, et al. Resection margins of 2 versus 5cm for cutaneous malignant melanoma with a thickness of 0.8 to 2.0mm[J]. Cancer, 1996, 77:1809
  • 5[5]Cohn-Cedermark G, Rutqvist LE, Andersson R, et al. Long term results of a randomized study by the Swedish Melanoma Study Group on 2-cm versus 5-cm resection margins for patients with cutaneous melanoma with a tumor thickness of 0.8-2.0 mm[J]. Cancer, 2000, 89:1495
  • 6[6]Cascinelli N, Morabito A, Sanrinami M, et al. Immediate or delayed dissection of regional nodes in patients with melanoma of the trunk: a randomised trial[J]. Lancet, 1998, 351:793
  • 7[7]Lane N, Lattes R, Malm J. Clinico-pathological correlation in a series of 117 malignant melanomas of the skin of adults [J].Cancer, 1958, 11:1025
  • 8[8]Lieber KA, Standiford SB, Kuvshinoff BW, et al. Surgical management of aberrant sentinel lymph node drainage in cutaneous melanoma[J]. Surgery, 1998,124:757
  • 9[9]Karp NS, Boyd A, Depan HJ, et al. Thoracotomy for metastatic malignant melanoma of the lung[J]. Surgery, 1990,107:256
  • 10[10]Petit T, Borel C, Rixe O, et al. Complete remission seven years after treatment for metastatic malignant melanoma [J].Cancer, 1996, 77:900

共引文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部