摘要
血栓性疾病是高发病率、高致残率、高死亡率疾病，严重危害人类健康。血小板是体内血栓形成的关键成分之一。血小板经骨髓巨核细胞脱落释放进入循环血，从而在心血管疾病（增殖、血栓形成和血栓栓塞）、炎症和部分肿瘤等多种病理生理进程中扮演重要角色。
出处
《中华心血管病杂志》
CAS
CSCD
北大核心
2012年第8期714-717,共4页
Chinese Journal of Cardiology
基金
国家自然科学基金（81172050）
四川省教育厅重点项目（10ZA034）
参考文献34
-
1Landry P, Plante I, Ouellet DL, et al. Existence of a microRNA pathway in anucleate platelets. Nat Struct Mol Biol, 2009, 16: 961-966.
-
2Ts'ao CH. Rough endoplasmic reticulum and ribosomes in blood platelets. Scand J Haematol, 1971, 8 : 134-140.
-
3Roth GJ, Hickey MJ, Chung DW, et al. Circulating human blood platelets retain appreciable amounts of poly (A) + RNA. Biochem Biophys Res Commun, 1989, 160 : 705-710.
-
4Evangelista V, Manarini S, Di Santo A, et al. De novo synthesis of cyclooxygenase-1 counteracts the suppression of platelet thromboxane biosynthesis by aspirin. Circ Res, 2006, 98: 593- 595.
-
5McRedmond JP, Park SD, Reilly DF, et al. Integration of proteomics and genomies in platelets: a profile of platelet proteins and platelet-specific genes. Mol Cell_ Pmteomics, 2004, 3: 133- 144.
-
6Hwang HW, Mendell JT. MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br J Cancer, 2006, 94 : 776-780.
-
7Tavazoie SF, Alarcon C, Oskarsson T, et al. Endogenous human microRNAs that suppress breast cancer metastasis. Nature, 2008, 451 : 147-152.
-
8Denis MM, Tolley ND, Bunting M, et al. Escaping the nuclear confines : signal-dependent pre-mRNA splicing in anucleate platel_ets. Cell, 2005, 122: 379-391.
-
9Bruchova H, Merkerova M, Prchal JT. Aberrant expression of microRNA in polycythemia vera. Haematologiea, 2008,93 : 1009- 1016.
-
10Kondkar AA, Bray MS, Leal SM, et al. VAMP8/endobrevin is overexpressed in hyperreaetive human platelets: suggested role for platelet microRNA. J Thromb Haemost, 2010, 8 : 369-378.
同被引文献43
-
1Roth GJ, Hickey MJ, Chung DW, et al. Circulatinghuman blood platelets retain appreciable amounts of poly(A)+ RNAQ]. Biochem Biophys Res Commun, 1989, 160(2): 705-710.
-
2Warshaw AL, Laster L, Shulman NR. Protein synthesis byhuman platelets[J]. J. Biol. Chem, 1967,242(9): 2094-2097.
-
3Lim LP, Glasner ME, Yekta S, et al. VertebratemicroRNA genes [J]. Science, 2003,299(5612): 1540.
-
4Hwang HW, Mendell JT. MicroRNAs in cellproliferation, cell death, and tumorigenesis [J]. Br J Cancer,2006,94(6): 776-800.
-
5Cheng AM, Byrom MW, Shelton J, et al. Antisenseinhibition of human miRNAs and indications for aninvolvement of miRNA in cell growth and apoptosis [J].Nucleic Acids Res, 2005, 33(4): 1290-1297.
-
6Landry P, Plante I, Ouellet DL, et al. Existence of amicroRNA pathway in anucleate platelets [J]. Nat StructMol Biol, 2009. 16(9): 961-966.
-
7Edelstein LC, Bray PF. MicroRNAs in platelet productionand activation[J]. Blood, 2011, 117(20): 5289-5296.
-
8Owens GK,Kumar MS,Wamhoff BR.Molecular regulation of vascular smooth muscle cell differentiation in development and disease[J].Physiol Rev,2004,84:767-801.
-
9Rzucidlo EM,Martin KA,Powell RJ.Regulation of vascular smooth muscle cell differentiation[J].J Vasc Surg,2007,45 Suppl A:A25-A32.
-
10Chang TC,Mendell JT.microRNAs in vertebrate physiology and human disease[J].Annu Rev Genomics Hum Genet,2007,8:215-239.
引证文献3
-
1罗茂,万沁,刘飞,马卫中,吴剑波.少白细胞血小板miRNA提取方法[J].泸州医学院学报,2013,36(2):117-120.
-
2曾敏,罗茂,李蓉,邓鑫,吴剑波.微小RNA调控血管平滑肌表型转化的研究进展[J].中华心血管病杂志,2014,42(9):793-796. 被引量：1
-
3罗宇霖,吴剑波,罗茂.血小板mRNA和微小RNA转移对血管细胞功能的影响[J].中华心血管病杂志,2018,46(2):161-164. 被引量：3
二级引证文献4
-
1潘孙雷,林辉,郭艳,翟小亚,郭航远,池菊芳.微小RNA-152介导叶酸对体外血管平滑肌细胞增殖迁移的抑制作用[J].营养学报,2017,39(5):484-488. 被引量：4
-
2马宏丰,石小哲.miR-146a在原发性肝癌组织中表达及对细胞增殖和侵袭的影响[J].中国现代普通外科进展,2018,21(12):930-933. 被引量：7
-
3刘淼,乌兰娜,张晓晓,李瑞珍.组织miRNA指标在宫颈癌的表达情况及其与病理分型、组织分化的相关性研究[J].重庆医学,2021,50(3):449-452. 被引量：5
-
4肖路,陈欣,童雪金.分析红细胞与血小板检测参数在糖尿病血管并发症中的检测价值[J].糖尿病新世界,2023,26(17):12-15.
-
1胡三觉,田巧莲.一种新的体内血栓形成动物模型[J].中华血液学杂志,1993,14(10):541-542. 被引量：55
-
2谢露,胡世凤,郭维坚.一种简易的体内血栓形成动物模型的研制[J].广西医科大学学报,2003,20(6):974-975. 被引量：5
-
3师秀云.骨髓巨核细胞蚕噬现象的观察[J].山西医学教育,2002(5):58-59.
-
4张芳,赵会英,马艳平.骨髓巨核细胞形态学分析[J].实用医技杂志,1998,5(6):365-365.
-
5张舟,王军平.ERK1/2对巨核细胞增殖分化和血小板生成的调控作用及研究进展[J].局解手术学杂志,2013,22(5):532-535.
-
6覃建民,张永梅,杨玉梅.BT87-3型实验性体内血栓形成测定仪使用技巧和应注意的问题[J].中国药理学通报,2005,21(6):755-756. 被引量：1
-
7刘晶莹,富丹.辛伐他汀预防性给药对高脂饮食大鼠体内血流动力学的影响[J].牡丹江医学院学报,2009,30(4):71-72.
-
8全媛,王平平.两种定量检测D-二聚体方法的比较[J].实验与检验医学,2013,31(5):504-505. 被引量：2
-
9血液与循环生理[J].国外科技资料目录（医药卫生）,1997(1):11-12.
-
10科学家发现形成血栓的细菌酶[J].医学信息,1997,0(9):14-14.
