424例新疆不同民族胃癌特征分析

The feature of 424 cases with gastric cancer of various nationalities in Xinjiang China

目的:了解近8年来就诊于我院的胃癌患者流行病学及临床病理资料的特点。方法:以我院2003年-2010年收治的行手术治疗的424例胃癌患者为研究对象,对其一般资料、病理类型、发生部位、临床分期等进行回顾性分析。结果:424例胃癌患者中,男女比为3.36∶1,年龄23-83岁,中位年龄61岁,高发年龄61-70岁。临床大体病理分型上,BorrmannⅡ型占大多数(78.77%);病理组织学类型以腺癌居多,占81.6%。分化程度以低、中分化为主。TNM临床分期中以Ⅲ期为主,占41.0%。民族分组分析发现汉族以胃下部(幽门、胃窦)多见,而维吾尔族偏上,以胃中部(胃体、胃角)多见;维吾尔族发病年龄较汉族相对提前,肿瘤大小较汉族大;维吾尔族肿瘤T分期,TNM分期较汉族晚。结论:胃癌老年男性易患,组织学病理类型以低、中分化腺癌多见。各民族组间的临床特征有所不同,在临床上应采取相应的诊疗措施。行手术治疗的大部分为中晚期患者,胃癌的早期诊断有待进一步提高。

Objective：To investigate the clinicopathologic and epidemiological characteristics of patients with gas-tric cancer at our hospital in the past eight years. Methods ： Data of 424 cases of gastric cancer patients from 2003 to 2010 in our hospital was retrospectively analyzed for their general information, tumor histological type, location, and clinical stage. Results：Among the 424 cases of gastric cancer patients, male to female ratio was 3.36：1 ;aged from 23 to 83 years old,with a median age of 61, most were from 61 to 70;Borrmann Ⅱ type was majority pathologic type （78.77%） ;adenocarcinoma was a majority histological type, accounting for 81.6% ;poorly and moderately differenti-ated cancer were most common. Stage Ⅲ was majority in clinical TNM staging, accounting for 41.0%. According to the ethnic group analysis, the cancer position was mainly on the lower part of stomach （pylorus, antrum） of Han, while that of Uighur was mainly upper to the stomach （gastric body, gastric angle） ;compared with Han, Uighur had an earlier age of bracket and larger size of tumor; Uighur＇s tumor T stage and TNM stage were relatively late compared with the Han. Conclusion：Elderly men are more susceptible to gastric cancer, mainly histological pathology to poorly and moderately differentiated adenocarcinoma;There are different clinical characteristics between the various Ethnic groups patients with gastric carcinoma. The majority of patients who underwent the surgical treatments have advanced or metastatic tumor, therefore it is necessary to improve the early diagnosis of gastric cancer.