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细胞间隙蛋白在乳腺癌中的研究进展 被引量：2

Advanced research on the connexins in breast cancer
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摘要 乳腺癌在女性恶性肿瘤发生中占据第一,细胞间隙蛋白家族被视为抑癌基因,在乳腺癌的增殖、侵袭和转移及化疗耐药中起重要的作用。本文主要讨论细胞间隙蛋白在乳腺癌中的研究进展,进而寻找细胞间隙蛋白与信号通路间的共通点,为乳腺癌的治疗打开新的研究方向。 Breast cancer has taken the first place in the women＇s malignant tumors. Connexin gene family is regarded as a tumor suppressor, playing an important role on the proliferation, invasion, metastasis and chemoresistenee of breast cancer. This review assesses our current understandings of the connexins and we want to find some common points with signaling pathways in order to open new research directions.
作者 傅韵 庄志刚
机构地区 同济大学附属第一妇婴保健院乳腺外科
出处 《现代肿瘤医学》 CAS 2012年第9期1953-1956,共4页 Journal of Modern Oncology
基金 上海市卫生局青年项目(编号:20114y155) 上海市申康前沿课题(编号:SHDC12010116)
关键词 细胞间隙蛋白 细胞间隙通讯 乳腺癌 化疗耐药 connexin GJIC breast cancer chemoresistance
分类号 R737.9 [医药卫生—肿瘤]
  • 相关文献

参考文献25

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二级参考文献11

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共引文献5

同被引文献12

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引证文献2

二级引证文献11

现代肿瘤医学
2012年 第9期

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