迪庆州健康人群首次麻疹抗体水平监测回顾分析

Retrospective analysis of first monitoring of measles antibody level among healthy population in Diqing prefecture

目的了解迪庆州健康人群麻疹免疫状况,为控制和消除麻疹提供指导。方法按云南省2009年人群麻疹抗体水平监测方案,该州2009年10月首次开展0～20岁健康人群的麻疹抗体监测工作,采用酶联免疫吸附试验(ELISA)测定麻疹IgG抗体。数据采用Excel软件处理,分4个年龄组进行统计,用描述性方法进行分析。结果①抗体阳性率为81.44%(733/900),年龄组差异有统计学意义(χ2=12.76,P<0.01);②有免疫史抗体阳性率为83.31%(704/845),年龄组差异有统计学意义(χ2=9.92,P<0.05);③无麻疹病史抗体阳性率为81.05%(710/876),年龄组差异有统计学意义(χ2=14.91,P<0.01)。结论结合免疫规划工作相关情况与该次抗体监测结果,表明迪庆州的麻疹预防控制形势依然十分严峻,应在保持常规免疫高接种率水平下进一步提高接种质量,并有计划地开展各年龄人群高质量的麻疹疫苗强化免疫活动。

[Objective]To understand the measles immunization status of healthy population in Diqing prefecture,and provide guidance for measles control and elimination.[Methods]According to ＂measles antibody level monitoring plan in Yunnan Province in 2009＂,measles antibody monitoring on healthy group aged 0-20 years was firstly implemented in this prefecture in October 2009.ELISA was used to determine measles IgG antibody.After treated by Excel,the data was classified into 4 age groups and analyzed with descriptive method.[Results] ① Antibody positive rate was 81.44%（733/900）,the difference between age groups was significant（χ2=12.76,P0.01）.② Antibody positive rate of individuals with immunization history was 83.31%（704/845）,with significant difference between age groups（χ2=9.92,P0.05）.③ That of individuals without immunization history was 81.05%（710/876）,with significant difference between age groups（χ2=14.91,P0.01）.[Conclusion]Immunization program and the antibody monitoring results show that measles control situation is still very severe in Dingqing prefecture.The vaccination quality should be further improved On the basis of high routine immunization rate,and the measles supplementary immunization should be carried out among all age groups prepensely.