中心静脉导管引流及注入胸腺法新联合顺铂治疗恶性胸腔积液86例疗效观察

Central venous catheter drainage and injection of thymalfasin combined with cisplatin in treatment of malignant pleural effusion:clinical observation of 86 cases

目的观察中心静脉导管注入胸腺法新联合顺铂治疗恶性胸腔积液的疗效及不良反应。方法选择恶性胸腔积液患者86例,胸腔中心静脉置管行闭式引流并腔内注入胸腺法新联合顺铂,每周1次。结果总有效率为83.7%,生活质量评分提高10～20分,不良反应少。结论中心静脉导管注入胸腺法新联合顺铂治疗恶性胸腔积液,疗效肯定,不良反应轻。

Objective To observe central venous catheter and injecting thymalfasin combined with cisplatin in treatment of malignant pleural effusion curative effect and adverse reaction. Methods 86 pa- tients with malignant pleural effusion, pleural cavity central venous catheter closed drainage and intraperi- cardial injection of thymalfasin combined with cisplatin, 1 times a week. Results the total effective rate was 83.72%, the score of life quality to improve 10-20, fewer adverse reactions. Conclusions central ve- nous catheter and injecting thymalfasin combined with cisplatin in treatment of malignant pleural effusion has definite curative effect, and adverse reaction to light.