1Van Gaal LF, Mertens IL, De Block CE. Mechanisms link- ing obesity with cardiovascular disease. Nature, 2006, 444 : 875 -880.
2Muniyappa R, Montagnani M, Koh KK, et al. Cardiovascu- lar actions of insulin. Endocr Rev, 2007, 28 : 463 -491.
3Sun MW, Zhong MF, Gu J, et al. Effects of different levels of exercise volume on endothelium-dependent vasodilation: roles of nitric oxide synthase and heine oxygenase. HypertensRes, 2008, 31:805 -816.
4Kleinbongard P, Schulz R, Rassaf T, et al. Red blood cells express a functional endothelial nitric oxide synthase. Blood, 2006, 107 : 2943 - 2951.
5Yang AL, Yeh CK, Su CT, et al. Aerobic exercise acutely improves insulin- and insulin-like growth factor-l-mediated vasorelaxation in hypertensive rats. Exp Physiol, 2011, 95 : 622 - 629.
6Owen KL, Pretorius L, McMullen JR, et al. The protective effects of exercise and phosphoinositide 3-kinase (p110ct) in the failing heart. Clin Sci, 2009, 116 : 365 -375.
7Heidarianpour A, Hajizadeh S, Khoshbaten A, et al. Effects of chronic exercise on endothelial dysfunction and insulin signaling of cutaneous microvascular in streptozoto- ein-induced diabetic rats. Eur J Cardiovasc Prey Rehabil , 2007, 14:746-752.
8Touati S, Meziri F, I)evaux S, et al. Exercise reverses met- abolic syndrome in high-fat diet-induced obese rats. Med Sci Sports Exerc, 2011,45 : 598 -407.
9Li QX, Xiong ZY, Hu BP, et al. Aging-associated insulin resistance predisposes to hypertension and its reversal by ex- ercise: the role of vascular vasorelaxation to insulin. Basic Res Cardiol, 2009,104 : 269 -284.
10Cacicedo JM, Gauthier MS, Lebrasseur NK, et al. Acute exercise activates AMPK and eNOS in the mouse aorta. Am J Physiol Heart Circ Physiol, 2011,301 : H1255 - H1265.
7Akiko Nanri,Kentaro Tomita,Yumi Matsushita,et al. Effect of six months lifestyle intervention in Japanese men with metabolic syndrome:randomized controlled trial[J]. Journal of Occupational Health, 2012,54 (3) : 215-222.
8Clare L Gillies,Keith R Abrams,Paul C Lambert,et al. Phar- macological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance:systematic review and meta-analysis[J]. BMJ,2007,334:299.
9Gu Yunjuan,Yu Haoyong,Li Yuehua,et al. Beneficial effects of an 8-week,very low carbohydrate diet intervention on obese subjects[J]. Evidence-Based Complementary and Alternative Med- icine, 20! 3 : 760804.
10Elisabetta Bacchi,Carlo Negri,Maria Elisabetta Zanolin,et al. Metabolic effects of aerobic training and resistance training in type 2 diabetic subjects[J]. Diabetes Care,2012,35(4):676-682.
