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1,25-二羟维生素D_3与2型糖尿病相关性研究进展 被引量：6

Progress in research of correlation between 1,25-dihydroxyvitamin D_3 and type 2 diabetes mellitus
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摘要 糖尿病是一种以糖代谢紊乱为主要表现的临床综合征,长期病程可引起多系统损害,导致血管、心脏、肾脏、神经等组织器官的慢性并发症。维生素D是经典的钙磷代谢调节剂,许多基础研究和动物实验显示维生素D具有保护胰岛B细胞、改善胰岛素抵抗和免疫调节作用。本文就近年来维生素D与2型糖尿病的相关性研究进展作一综述。
作者 刘建萍 母义明
机构地区 解放军总医院内分泌科 江西省人民医院
出处 《军医进修学院学报》 CAS 2012年第9期989-991,共3页 Academic Journal of Pla Postgraduate Medical School
基金 国家"863"计划项目(2011AA020113)~~
关键词 1 25-二羟维生素D3 2型糖尿病 胰岛素抵抗 大血管并发症 微血管并发症
分类号 R587.1 [医药卫生—内分泌]
  • 相关文献

参考文献32

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二级参考文献11

  • 1高建军,周轶,顾淑珠,金慰芳,王洪复.大鼠骨生物学指标的月龄特征[J].中国骨质疏松杂志,2004,10(2):143-146. 被引量：9
  • 2杨定焯,程静,安珍.建立原发性骨质疏松症诊断标准的原则和方法[J].中国骨质疏松杂志,1999,5(2):36-40. 被引量：12
  • 3郭世钹,罗先正,邱贵兴,主编.活性维生素D与骨质疏松症.天津:天津科技出版社,2001.461-473.
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  • 6Norman AW, Frankel JB, Heldt AM ,et al. Vitamin D deficiency inhibits pancreatic secretiou of insulin[ J ]. Science, 1980, 209 (4458) :823-825.
  • 7Bourlon PM, Faure-Dussert A, Billaudel B. The de novo synthesis of numerous proteins is decreased dining vitamin D3 deficiency and is gradually restored by 1, 25-dihydroxyvitamin D3 repletion in the islets of Langerhans of rats [ J ]. J Endocrinol, 1999,162 ( 9 ) : 101-109.
  • 8Borissova AM, Tankova T, Kirilov G, et at. The effect of vitamin D3 on insulin secretion and peripheral insulin sensitivity in type 2 diabetic patients[ J ]. Int J Clin Pract, 2003,57 (4) :258-261.
  • 9陆泽元,廖二元,伍贤平,伍汉文,周智广,邓小戈.去卵巢对大鼠骨密度的影响[J].中国骨质疏松杂志,2002,8(1):13-15. 被引量：13
  • 10刘杰,苗懿德.老年男性2型糖尿病患者骨质疏松与各种钙调激素的关系研究[J].中国老年学杂志,2003,23(7):428-429. 被引量：13

共引文献13

同被引文献83

  • 1Getoff N .Vitamin-induced intracellular electrons are the mechanism for their well-known beneficial effects [J]. Nutrition, 2013, 29 (4): 597-604.
  • 2Weisman Y. Non-classic unexpected functions of vitamin D [J]. Pediatr Endocrinol Rev, 2010, 8 (2) : 103-107.
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引证文献6

二级引证文献26

军医进修学院学报
2012年 第9期

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