心脉隆注射液治疗老年慢性心力衰竭的临床观察

Effects of Xinmailong injection in aged patients with chronic heart failure

目的:观察心脉隆注射液治疗慢性心力衰竭(CHF)的效果。方法:46例CHF患者被随机分为常规治疗组(21例,常规抗心力衰竭治疗)和心脉隆治疗组(25例,在常规抗心衰治疗基础上加用心脉隆注射液)。疗程2周,在用药前、用药后1～2周进行6min步行试验并进行超声心动图检查。结果:治疗2周后,心脉隆组总有效率明显高于常规治疗组(92.0%比61.9%);两组患者6min步行距离及LVEF均有明显改善(P<0.05或<0.01),且与常规治疗组比较,心脉隆组6min步行距离[(416.00±39.25)m比(475.00±42.11)m]明显增加,LVEF[(41.23±6.75)%比(48.35±7.5)%]明显提高,P均<0.05。结论:心脉隆注射液是治疗老年慢性心力衰竭有效的辅助用药。

Objective：To observe effect of Xinmailong injection on chronic heart failure（CHF）.Methods： A total of 46 CHF patients were randomly divided into routine treatment group（n=21,received routine treatment of anti-heart failure） and Xinmailong group（n=25,received Xinmailong injection based on routine treatment of anti-heart failure）.Treatment period was two weeks.All patients underwent 6min walking test and echocardiography before and 1～2 weeks after treatment.Results：After treatment two weeks,total effective rate of Xinmailong group was significantly higher than that of routine treatment group（92.0% vs.61.9%）;there were significant improvement in 6min walking distance（6MWD） and left ventricular ejection fraction（LVEF） in both groups（P0.05 or 0.01）.Compared with routine treatment group,there were significant increase in 6MWD [（416.00±39.25） m vs.（475.00±42.11） m]and LVEF [（41.23±6.75）% vs.（48.35±7.5）%]in Xinmailong group,P0.05 both.Conclusion： Xinmailong injection is an effective auxiliary drug for treatment of chronic heart failure in aged patients.