骨关节结核患者外周血T细胞亚群的研究

A study on T cells subsets in peripheral blood of pat. ients with osteoarticular tuberculosis

采用SOKT系列抗人T淋巴细胞单克隆抗体,以直接SPA菌体花环法对19例骨关节结核患者外周血T细胞及亚群的分布进行了研究。结果表明,患者组SOKT_^+细胞略有降低(P>0.05)、SOKT_4^+细胞明显降低(P<O.05)、S0KT_^+细胞无改变,SOKT_4/SOKT_比值显著降低(P<0.02),提示骨关节结核患者细胞免疫功能受抑。

Utilizing the monoclonal T.lymphocyte antibodies and direct SPA rosette technique,the authors studied the percentage of T.lymphocyte subsets in peripheral blood of 12 patients with osteoarticular tuberculosis in the paper.The results showed that the SOKT_3^+ of the patients reduced slightly (p>0.05),the SOKT_4^+ and the ratio of SOKT_4 and SOKT_8 significantly(respectively p<0.05 and p<0.02) and the SOKT_8^+ did not change.This suggested that the cellular immune function of the patients was inhibited.