缺血性中风患者中医辨证分型与脑血管造影结果相关性研究

Correlative Study on the Pattern/Syndrome Differentiation in Traditional Chinese Medicine and the Outcomes of Cerebral Angiography for the Patients with Ischemic Apoplexy

目的探讨缺血性中风患者脑血管病变范围及狭窄程度与中医证型的关系,寻求辨证防治缺血性中风的客观化指标。方法选取进行脑血管造影的缺血性中风患者86例,对比分析脑血管病变范围及狭窄程度与中医证型的关系。结果脑血管狭窄组的风痰瘀阻型和气滞血瘀型比例均高于脑血管正常组(P<0.05),而脑血管正常组的风痰火亢型比例高于脑血管狭窄组(P<0.05),其他各组各证型之间比较,差异无统计学意义(P>0.05)。多支病变组风痰瘀阻型、气滞血瘀型比例均高于无病变组和单支病变组(P<0.05),其他各组各证型之间比较,差异无统计学意义(P>0.05)。结论缺血性中风的造影结果不同证型特点不同,风痰瘀阻型、气滞血瘀证随着脑血管病变范围的增大、狭窄程度的增加,所占的比例明显增多。

Objective To discuss the relationship of the patterns/syndromes in traditional Chinese medicine with the cerebral vascular lesion scope and stenosis severity for the patients with ischemic apoplexy and explore the objective indexes for the pattern/syndrome differentiation, prevention and treatment of ische mic apoplexy. Methods 86 cases of ischemic apoplexy and undergoing cerebral angiography were selected. In comparison, the relationship of the cerebral vascular lesion scope and stenosis severity was analyzed in terms of the patterns/syndromes of traditional Chinese medicine. Results The proportion of either wind phlegm stagnation pattern/syndrome or qi and blood stagnation pattern/syndrome in the group of cerebral vas cular stenosis was higher than that in the normal cerebral vascular group（ P 〈 0.05 ）. In the normal cerebral vascular group, the proportion of wind phlegm and fire hyperactivity pattern/syndrome was higher than that in the cerebral vascular stenosis group（ P 〈 0.05 ）. The differences among the other patterns/syndromes were not statistically significant in comparison （P 〉 0.05 ）. In the multi vessel lesion group, the proportion of either wind phlegm stagnation pattern/syndrome or qi and blood stagnation pattern/syndrome was higher than that in the no vessel lesion group and the single vessel lesion group（ P 〈 0.05 ）. The differences among the other patterns/syndromes were not statistically significant in comparison （ P 〉 0.05 ）. Conclusion The outcomes of angiography are relevant with the different characteristics of the patterns/syndromes of ischemic apoplexy. The proportions of wind phlegm stagnation pattern/syndrome and qi and blood stagnation pattern/syndrome are getting higher obviously with the increase of the cerebral vascular lesion scope and the stenosis severity.