逍遥丸联合干扰素-a治疗慢性乙型肝炎的临床观察

Clinical observation of treating chronic hepatitis B with Xiaoyao pills plus interferon-a

目的:观察逍遥丸联合干扰素-a治疗慢性乙型肝炎的临床疗效。方法:根据病毒性肝炎诊断标准选择初诊慢性乙型肝炎患者,血清学检查符合干扰素-a用药指征,治疗组给予逍遥丸联合干扰素-a,对照组单用干扰素-a,疗程均为48周。结果:治疗组可以较快改善症状、体征、肝脏炎症(P<0.05)、降低病毒载量(P<0.05)。结论:逍遥丸联合干扰素-a治疗慢性乙型肝炎患者具有较好的临床疗效,优于单用干扰素-a,可改善临床症状,提高临床疗效,并可减轻干扰素-a的副作用。

Objective： To observe the clinical effect of treating chronic hepatitis B with Xiaoyao pills plus interferon-a. Methods： Viral hepatitis diagnostic criteria for selection of newly diagnosed patients with chronic hepatitis B serological tests in line with interferon-a drug indication, the treatment group was treated with the Xiaoyao pills plus interferon-a, and the control group alone was given interferon-a for treatment, 48 weeks as a course. Results： The treatment group can rapidly improve the symptoms, signs, inflammation of the liver （P〈0.05）, lower viral load （P〈0.05）. Conclusion： Treating chronic hepatitis B with Xiaoyao pills plus interferon-a has better clinical efficacy superior to interferon-a, can improve clinical symptoms, improve clinical outcomes and reduce the side effects of interferon-a.