新疆地区哈萨克族成年人心脏瓣膜病患病率调查

The Prevalence Study of Valvular Heart Disease in Xinjiang Kazakh Adult Population

目的:了解新疆哈萨克族成年人心脏瓣膜病(VHD)患病率及其分布特征。方法:采用四阶段整群随机抽样法,对新疆7个地区35岁以上哈萨克族成年人进行心脏瓣膜病流行病学调查。结果:新疆哈萨克族成年人VHD患病率为12.3%,其中男性患病率为11.8%,女性患病率为12.8%,性别差异无统计学意义(P>0.05);城镇患病率为12.5%,农牧区为12.2%,城乡差异无统计学意义(P>0.05);所有瓣膜病变中,单纯主动脉瓣病变占25.8%,二尖瓣病变占52.7%,单纯主动脉瓣病变+二尖瓣病变占21.5%。结论:新疆哈萨克族成年人VHD患病率高于同地区的汉族与哈萨克族,瓣膜病变中以二尖瓣受累最多见。

Objective： To investigate the prevalence and epidemiological features of valvular heart disease（VHD） in Kazakh adult population in Xinjiang. Method： A total of 4094 adults aged 35 or older were surveyed. Random sampling was employed to study valvular heart disease in different age, gender and urban and agricultural groups. Samples were collected from 7 localities in Xinjiang. Result： The prevalence rate of valvular heart disease in Xinjiang Kazakh adult population was 12.3%, the differences of prevalence of valvular heart disease among different gender groups, urban and agricultural areas were no statistically significant（P〉0.05）. In all of the valvular heart disease, aortic valve alone accounted for 25.8%, of mitral（52.7%）, of aortic ＋ mitral valve（21.5%）. Conclusion： The prevalence of valvular heart disease is higher in Kazakh than that in Uygur and HaM people. Among all of valvular disease, mitral valve involvement is most common.