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霍乱动力学模型中的基本再生数的计算和稳定性分析 被引量:2

THE BASIC REPRODUCTION NUMBER FOR THE CHOLERA OUTBREAK
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摘要 本文旨在通过2008年2009年津巴布韦爆发的严重霍乱疫情建立的数学模型来计算基本再生数以及进行稳定性分析.我们首先建立ODE模型并推出两个重要参数β_H和β_L的值,再进行数值模拟使得其预测结果完全吻合津巴布韦的实际疫情,其后通过此ODE模型的再生矩阵计算基本再生数并进行稳定性分析,并且通过计算出的基本再生数值得到一些预防和控制霍乱的有效方法. In this paper, we aim to estimate the basic reproduction number R0 for the most recent cholera outbreak (2008-2009) in Zimbabwe. This study is based on the mathematical cholera model developed in [6], and it is found that the model can well fit the Zimbabwean cholera data. We formally derive R0 by computing the next generation matrix as well as conducting a stability analysis. The resulting value of R0 qualitatively agrees with those obtained by other means. Some applications of this estimate to the prevention and treatment of Zimbabwean cholera epidemics are briefly discussed.
出处 《数值计算与计算机应用》 CSCD 2012年第3期189-197,共9页 Journal on Numerical Methods and Computer Applications
基金 国家自然科学基金数学天元青年基金(No.11126333) 重庆市科委自然科学基金资助项目(编号:CSTC 2011BB0104) 重庆工商大学科研启动基金项目(编号:2011-56-03 2011-56-02)
关键词 霍乱 基本再生数 无病平衡点 稳定性分析 津巴布韦 Cholera the basic reproduction number equilibrium stability analysis Zimbabwean
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