重症肺炎肌酶检测临床意义

Clinical significance of detection of myocardial enzymes in patients with severe pneumonia

目的研究肌酶在重症肺炎的变化特点及临床诊断价值。方法选择356例肺炎患者为研究对象，其中152例重症肺炎设为重症肺炎组，204例普通肺炎设为普通肺炎组，并以56例正常体检人员为对照，比较三组别肌酶的差异及重症肺炎组肌酶正常患者与异常患者的血气分析特点，研究重症肺炎组中不同病原体感染引起的肌酶谱、C反应蛋白变化特征。结果AST、LDH、a—HBDH、CK、CK—MB三组经方差分析，差异有统计学意义（P〈0．05）；重症肺炎组中心肌酶正常患者与异常患者的血气分析经t检验分析，差异有统计学意义（P〈0．05），重症肺炎引起组织损害以病毒比较常见。结论肌酶是重症肺炎合并组织损害、心力衰竭早期诊断比较灵敏的监测指标，心肌损害的早期诊断、早期治疗对疾病的预后有重要的临床意义。

Objective To study myocardial enzyme spectrum in severe pneumonia characteristics and clinical diagnosis value. Methods 356 cases of patients with pneumonia as the object of study, including 152 cases of severe pneumonia with severe pneumonia group,204 cases of pneumonia is common pneumonia group, and in 56 normal physical examination personnel as control, were compared between the three groups of myocardial enzymes between severe pneumonia group and myocardial enzymes in patients with normal and abnormal in patients with blood gas analysis features, research severe pneumonia group different pathogen infection caused by myocardial enzyme spectrum, C reactive protein variation characteristics. Results Three groups of AST, LDH, HBDH, CK, CK-MB alpha by analysis of variance, there was statistically significant difference （P 〈 0.05 ）, severe pneumonia group of myocardium enzymes in normal patients and patients with abnormal blood gas analysis by t test analysis, there was significant difference （ P 〈0.05）, and severe pneumonia, myocardial damage caused by the virus are more common in. Conclusions Myocardial enzyme is severe pneumonia complicated with heart failure in early diagnosis of myocardial damage, more sensitive monitoring index, myocardial damage in the early diagnosis, early treatment on the prognosis of the disease has important clinical significance.