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子宫内膜异位症患者对氧磷酶-1和氧化低密度脂蛋白水平分析 被引量:1

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摘要 目的探讨子宫内膜异位症患者血清对氧磷酶-1(PON1)活性和氧化低密度脂蛋白(OX—LDL)水平的变化,揭示子宫内膜异位症发病机制与氧化应激的关系。方法将46例子宫内膜异位症患者和40例健康体检妇女作为研究对象,测定血清中PON1活性和ox—LDL水平。将46例子宫内膜异位症患者分期,比较各期患者血清中PON1活性和OX-LDL水平。结果子宫内膜异位症患者组血清PON1活性低于对照组,差异有统计学意义(P〈0.01);ox-LDL水平高于对照组,差异有统计学意义(P〈0.01)。不同分期的子宫内膜异位症患者血清PON1和ox-LDL的水平,差异无统计学差异(P〉0.05)。血清PON1活性和ox—LDL水平呈负相关(r=-0.5347,P〈0.01)。结论子宫内膜异位症的发生、发展与氧化应激相关。
出处 《中国实用乡村医生杂志》 2012年第16期48-49,共2页 Chinese Practical Journal of Rural Doctor
基金 【基金项目】本文受沈阳医学院2011年学院青年基金资助,课题编号:20112059.
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