摘要
狼疮足细胞病是指系统性红斑狼疮导致的肾小球足细胞病,其临床表现为肾病综合征,病理改变以肾小球足细胞足突广泛融合为特征,伴或不伴有系膜细胞或系膜基质增生,除肾小球系膜区免疫复合物沉积外,毛细血管袢内皮下及上皮侧均无免疫复合物沉积。本文对近年来国外有关狼疮足细胞病的研究进展加以综述。
Lupus podocytopathy is characterized by nephrotic syndrome and diffuse foot process effacement of podocyte with or without mesangial immune deposits hut in the absence of subendothelial and subepitheliaJ immune complex deposits in SLE patients. In this review, we will discuss recent progress on the clinical-pathlogical features and mechanisms of the lupus podoeytopathy.
出处
《肾脏病与透析肾移植杂志》
CAS
CSCD
北大核心
2012年第4期375-378,共4页
Chinese Journal of Nephrology,Dialysis & Transplantation
关键词
系统性红斑狼疮
足细胞病
进展
systemic lupus erythematosus podocytopathy review