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2型糖尿病非酒精性脂肪肝患者visfatin水平与相关因素分析 被引量:2

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摘要 目的探讨visfatin与2型糖尿病(T2DM)及其非酒精性脂肪肝(NAFLD)并发症和相关代谢指标的关系。方法将80例T2DM患者分为合并NAFLD组50例和单纯T2DM组30例,并选30例健康人做对照。所有的受试者均采用酶联免疫测定法(ELISA)测定空腹血清visfatin浓度;并测定各组的人体指标和血代谢指标水平;并分析各指标间及与NAFLD并发症的相关性。结果①T2DM合并NAFLD组、单纯T2DM组及对照组间相互比较血清visfatin浓度差异无显著性(P=0.874;P=1.000)。②相关分析显示,T2DM组血清visfatin浓度与WC、TG均呈正相关。③多元线性逐步回归分析显示,TG是血清visfatin独立相关因素。结论血清visfatin浓度在合并非酒精性脂肪肝的2型糖尿病中无明显变化,但与腹型肥胖及高甘油三酯血症密切相关。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2012年第17期3637-3638,共2页 Chinese Journal of Gerontology
基金 贵阳市科技局立项项目〔No.2009筑科农合同字3-006号〕
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参考文献9

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二级参考文献14

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