多排螺旋CT冠状动脉成像评价冠状动脉病变与Framingham评分的关系

Evaluation on relation between coronary lesions and Framingham risk score with multi-detector CT coronary angiography

目的探讨MDCT冠状动脉成像(MDCTCA)与传统Framingham危险评分(FRS)之间的关系。方法 415例临床可疑或已知冠心病患者接受MDCTCA检查。冠状动脉按照狭窄程度分为狭窄≥50%、狭窄<50%和正常。对患者进行FRS,根据FRS将患者分为低度危险组、中度危险组和高度危险组。比较3组间发生冠状动脉狭窄及斑块类型的差异。结果 根据FRS,低度、中度、高度危险组患者分别占36.63%(152/415)、39.28%(163/415)、24.10%(100/415)。冠状动脉CTA正常患者在低度、中度、高度危险组中分别占72.37%(110/152)、46.63%(76/163)、36.00%(36/100)。低度、中度、高度危险组的患者中冠状动脉狭窄≥50%者分别占6.58%(10/152)、23.31%(38/163)、40.00%(40/100),3支冠状动脉病变发病率分别为0.66%(1/152)、3.07%(5/163)、5.00%(5/100),差异均有统计学意义(P<0.05)。不同FRS之间冠状动脉斑块类型发生率差异无统计学意义。结论 MDCTCA能够提供有关冠状动脉解剖学改变以外的信息。

Objective To explore the relation between coronary lesions with MDCT coronary angiography （MDCTCA） and Framingham risk score （FRS）. Methods Totally 415 patients with suspected or known coronary artery disease underwent MDCTCA examination. The severity of the atherosclerosis were classified by ≥50% luminal narrowing, 〈500% lu minal narrowing and normal in major vessel using MDCTCA. According to the FRS, all patients were divided into low, in termediate and high risk group. The differences of coronary stenosis and the type of plaques were analyzed among groups. Results According to the FRS, the patients in low, intermediate and high risk group were 36.63% （152/415）, 39.28% （163/415） and 24.10% （100/415） respectively. The patients with normal coronary arteries were 72.37% （110/152）, 46.63% （76/163）, 36.00% （36/100）, respectively in low, intermediate and high risk group. The patients with coronary stenotic ≥50% were 6.58% （10/152）, 23.31% （38/163） and 40.00% （40/100）, furthermore three branches disease were 0. 66% （1/152）, 3.07% （5/163） and 5.00% （5/100）, respectively in low, intermediate and high risk group, which had statistical difference （P〈0.05）. But there was no statistical difference between three groups in the type of plaque.