褪黑素胶囊改善睡眠功能实验研究

Study on sleep improvement by Melatonin capsule

目的研究褪黑素胶囊对小鼠睡眠改善功能。方法通过直接睡眠实验、延长戊巴比妥钠睡眠时间实验、戊巴比妥钠阈下剂量催眠实验、巴比妥钠睡眠潜伏期实验,观察褪黑素胶囊对小鼠睡眠功能的影响。结果褪黑素胶囊无直接睡眠作用,能显著延长戊巴比妥钠睡眠时间、协同戊巴比妥钠阈下剂量催眠作用、对巴比妥钠睡眠潜伏期无明显影响。结论褪黑素胶囊具有改善睡眠的功效。

Objective To observe the effect of sleep improvement of Melatonin capsule.Methods The effect of Melatonin capsule were observed through experiments of sleep induced directly,prolonging sleeping time induced by pentobarbital sodium,affecting sleeping rate under the threshold hypnogenesis dosage of pentobarbital sodium,sleep delitescence induced by tobarbital sodium.Results Melatonin capsule had no direct effect on sleep,but can prolong sleeping time induced by pentobarbital sodium,and significantly increase the incidence of sleeping animals.Conclusion The Melatonin capsule can improve sleep function.