肝病性糖尿病的发病机制及治疗进展

The Pathogenesis and the Advance in Treatment of Hepatogenic Diabetes

肝源性糖尿病为继发性糖尿病,因肝实质损害而导致,患者以餐后高血糖和葡萄糖耐量减低为特征。发病机制与肝病时肝糖原合成能力降低,胰岛素抵抗有关。治疗原则是改善和保护肝功能,降低高血糖,缓解症状。所以该病在诊治方面与2型糖尿病有很大区别,本文在此综述如下。

Hepatogenic diabetes is secondary diabetes caused by liver parenchyma damage, patients are with postprandial hyperglycemia and reduce glucose tolerance for features. It has the relationship among pathogenesis and the liver glycogen synthesis capacity reduction and insulin resistance. The principle of treatment is to improve and protect liver function, re- duce hyperglycemia and relieve symptoms. So the hepatogenic diabetes is different from the type 2 diabetes in diagnosis and treatment, this paper is in the review as follows.