放射性肺炎使用大剂量维生素C治疗的临床观察

Clinical observation on application of high-dose vitamin C in patients with radiation pneumonia

目的:探讨大剂量维生素C对放射性肺炎的治疗效果。方法:选取肺癌放疗后引起放射性肺炎2、3、4级患者50例,随机分为观察组和对照组。对照组在治疗期间予常规口腔护理、吸氧、激素辅助治疗及营养支持治疗,3级以上加用氨茶碱治疗。治疗组在对照组的基础上加用维生素C3.0g/d静脉注射,14d后比较治疗效果。结果:观察组有效率优于对照组(P<0.05)。结论:大剂量维生素C治疗肺癌放疗后放射性肺炎有效。

Objective ： To observe the efficacy of high-dose vitamin C on radiation pneumonia. Methods ： Fifty patients with lung cancer, complicating 2, 3 and 4 degree of radiation pneumonia were randomly divided into treatment group and control group. Patients in control group were given routine oral care, oxygenaton, hormone therapy and nutritional support- ive treatment, while those with more than 3 degree of radiation pneumonia aminophylline was used. Patients in treatment group received vitamin C （3.0g/qd） intravenously based on the treatment of control group. The effects were compared after 14 days. Results： The efficiency of high dose vitamin C in treatment of radiation pneumonia is superior to that of control group （P 〈 0.05 ）. Conclusion： High-dose vitamin C is effective for radiation pneumonia in patients with lung cancer caused by radiotherapy.